Evidence map›Paper›PMID 40688019›Full record

ArticleBioactive materials2025

Anti-fatigue adhesive non-swelling hydrogel constructed by covalent topological structure and micro-nano gel for stretchable bioelectronics.

Gongwei Tian, Ming Zhu, Jianhui Chen, Cuiyuan Liang, Qinyi Zhao, Dan Yang, Yan Liu, Shuanglong Tang, Jianping Huang, Zhiyuan Liu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gongwei TianMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Ming ZhuMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Jianhui ChenMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Cuiyuan LiangMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Qinyi ZhaoMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Dan YangMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Yan LiuMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Shuanglong TangMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Jianping HuangBiomedical Microdevices Research Laboratory, Shenzhen Institutes of Advanced Technology, The Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen, 518055, PR China.
Zhiyuan LiuBiomedical Microdevices Research Laboratory, Shenzhen Institutes of Advanced Technology, The Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen, 518055, PR China.
Weihong LuMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.
Meifang ZhuState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.
Wei YanState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.
Dianpeng QiMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogel adhesives are rapidly emerging as a promising candidate toward flexible bioelectronics due to their adhesive characteristics and tissue-like mechanical properties. However, current hydrogel adhesives manifest weak anti-fatigue adhesion and an inability to ensure long-term integration of bioelectrodes on wet and dynamic tissue surfaces because they are constrained by their high swelling ratio and exclusive formation of covalent bonds at the tissue interface and its own weak cohesion. Here, we for the first time develop covalent bond topological adhesion paired with double covalent bond cross-linking in hydrogel to enhance cohesive force and adhesive force, achieving excellent anti-fatigue tissue adhesion and adhesive's capacity to follow significant tissue deformation. The adhesive strength of our hydrogel (Sodium alginate-polyacrylamide-acrylic acid N-hydroxysuccinimide ester hydrogel (SPAN) as the substrate and liquid adhesive containing chitosan (LC) as the adhesive layer) reaches impressive 290 kPa, surpassing that of the reported hydrogels (∼130 kPa). Additionally, fatigue threshold of SPAN/LC adhesion (240 J m

Indexed as

Anti-fatigue adhesionCovalent bond topologyFlexible bioelectronicsHydrogel adhesivesLong-term integration

Identifiers

PMID40688019
PMCPMC12274688

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.