A Rare Case of Adult Embryonal Rhabdomyosarcoma of the Uterus in a Postmenopausal Woman.

Rhabdomyosarcoma is a malignant soft tissue tumor arising from undifferentiated myogenic progenitor cells, predominantly occurring in children. Here, we report a peculiar case of adult rhabdomyosarcoma of the uterus in a postmenopausal lady, who presented with heaviness in the lower abdomen and a large abdominopelvic mass. In this article, we discuss the difficulty in diagnosing such cases and the crucial role of immunohistochemistry. This case report highlights the importance of considering rhabdomyosarcoma as a differential diagnosis in atypical soft tissue tumors, especially in postmenopausal women. Rhabdomyosarcoma of the uterus in adults being very rare, there is limited data on the appropriate management guidelines. Our patient received multimodality treatment with surgery followed by palliative chemotherapy and radiotherapy for recurrence of the disease. As rhabdomyosarcoma is very aggressive, prognosis is often poor. Hence, early diagnosis and prompt initiation of multidisciplinary treatment offer the best chance of survival for these patients.