Evidence map›Paper›PMID 40687855›Full record

ArticleFrontiers in microbiology2025

An optimised promoter and signal peptide improves methionine production of a genetically engineered

Qiburi He, Shaofeng Su, Riqilang Ao, Lingli He, Xiao Wang, Mei Chun, Gaowa Gong

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiburi HeInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Shaofeng SuInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Riqilang AoInner Mongolia Normal University, Hohhot, China.
Lingli HeHulunbuir Vocational Technical College, Hulunbuir, China.
Xiao WangInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Mei ChunInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Gaowa GongInner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: L-methionine is nutritionally indispensable for humans and animals. It is widely applied to feed, livestock and poultry breeding, food, medicine, energy and chemical industries. Maize endosperm contains a stable protein called Methods: In this study, we aimed to improve methionine yields in an engineered Results: Finally, a secretory expression system pGS-zein containing a strong promoter GP6 and an optimal signal peptide SP8 was constructed. In the food-grade engineered Discussion: This study demonstrates successful expression and secretion of

Indexed as

Candida utilisexpression vectormethioninepromotersignal peptides

Identifiers

PMID40687855
PMCPMC12271212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.