Evidence map›Paper›PMID 40687784›Full record

ArticleiScience2025

Interleukin-6 in synovial fluid drives the conversion of DC2s to DC3s in inflammatory arthritis.

Annika H Decker, Lucas L van den Hoogen, Tom van Oorschot, Liliana Sanchez-Rocha, Martine A Boks, Ghaith Bakdash, Ranjeny Thomas, Calin D Popa, Martijn Verdoes, Rogier M Thurlings and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Annika H DeckerMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Lucas L van den HoogenRheumatology, Sint Maartenskliniek 6574 NA Ubbergen, the Netherlands.
Tom van OorschotMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Liliana Sanchez-RochaMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Martine A BoksFrazer Institute, The University of Queensland, Brisbane, QLD 4102, Australia.
Ghaith BakdashMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Ranjeny ThomasFrazer Institute, The University of Queensland, Brisbane, QLD 4102, Australia.
Calin D PopaRheumatology, Sint Maartenskliniek 6574 NA Ubbergen, the Netherlands.
Martijn VerdoesMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Rogier M ThurlingsRheumatology, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
Anouk M D BeckerMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
I Jolanda M de VriesMedical BioSciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory arthritis (IA) is characterized by persistent joint inflammation and immune cell infiltration, including CD1c

Indexed as

Components of the immune systemImmune responseImmunology

Identifiers

PMID40687784
PMCPMC12270937

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.