Evidence map›Paper›PMID 40687714›Full record

SynthesisFrontiers in medicine2025

Association of

Jiwen Du, Weiting Shen, Zhenting Zhou, Qiuyan Wu, Zongyao Ai

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. New Insights into CRISPR-like Arrays inPathogens (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiwen DuDepartment of Gastroenterology, Wuxing District People's Hospital, Wuxing District Maternal and Child Health Hospital Huzhou City, Zhejiang, China.
Weiting ShenDepartment of Pneumology, Wuxing District People's Hospital, Wuxing District Maternal and Child Health Hospital Huzhou City, Zhejiang, China.
Zhenting ZhouDepartment of Neurology, Huzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine, Huzhou, China.
Qiuyan WuDepartment of Neurology, Huzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine, Huzhou, China.
Zongyao AiDepartment of Neurology, Huzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine, Huzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The pathogenesis of neurodegenerative diseases is complex, involving multiple factors, including genetic, environmental, and lifestyle elements. Recent studies have suggested that infectious agents may act as important triggers for neurodegenerative diseases. This study aimed to evaluate the association between Methods: A systematic search was conducted across the PubMed, Embase, and Cochrane Library databases for studies published up to December 2024. The combined effect sizes were expressed as odds ratios (OR) with 95% confidence intervals (CI) and were calculated using a random-effects model. Further exploratory analyses included sensitivity analyses, subgroup analyses, and assessment of publication bias. Results: Forty-one studies involving 159,220 participants were selected for the meta-analysis. We found that Conclusion: This study found that Systematic review registration: INPLASY (INPLASY202510044).

Indexed as

all-cause dementiaAlzheimer’s diseaseHelicobacter pylori infectionmeta-analysismultiple sclerosisParkinson’s disease

Identifiers

PMID40687714
PMCPMC12271219

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.