Evidence map›Paper›PMID 40687620›Full record

ArticleJournal of structural biology: X2025

Indel-driven evolution of the canavanine tRNA-editing deacetylase enzyme CtdA.

Nino Tabagari, Franziskus Hauth, Jennifer R Fleming, Jörg S Hartig, Olga Mayans

Abstract read
In one paragraph

Article in Journal of structural biology: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nino TabagariDepartment of Biology, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
Franziskus HauthDepartment of Chemistry, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
Jennifer R FlemingDepartment of Biology, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
Jörg S HartigDepartment of Chemistry, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.
Olga MayansDepartment of Biology, University of Konstanz, Universitätsstraße 10, 78457 Konstanz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins are heteropolymers composed of twenty standard amino acids, but over 500 non-proteogenic amino acids exist in nature that can be misincorporated into proteins. Canavanine is an antimetabolite of the chemically similar L-arginine. It can be utilized by bacteria such as

Indexed as

Indel-mediated fold evolutionSite directed mutagenesistRNA-editingX-ray crystallography

Identifiers

PMID40687620
PMCPMC12268091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.