Evidence map›Paper›PMID 40687619›Full record

ReviewObstetric medicine2026

Inherited aortopathies and risk of aortic dissection and aortic syndrome in pregnancy.

Timothy Chalk, Kylie Burns, Adam Morton

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Obstetric medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy ChalkCardiology Department, The Prince Charles Hospital, Chermside, Queensland, Australia.ORCID https://orcid.org/0000-0003-2111-8625
Kylie BurnsCardiology Department, The Prince Charles Hospital, Chermside, Queensland, Australia.
Adam MortonFaculty of Medicine, The University of Queensland, Herston, Queensland, Australia.ORCID https://orcid.org/0000-0001-9887-714X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute aortic dissection related to pregnancy is rare, however represented the third most common cause of pregnancy-related cardiovascular death in the 2017 UK-MBBRACE report. The majority of women with pregnancy-related aortic dissection have an underlying inherited syndromic aortopathy, though this is often not recognised until an event. Data regarding the immediate and long-term effects of pregnancy on aortic outcome are not uniform due to publication and ascertainment biases, small sample sizes, inclusion of women whose dissection was the first presentation of the underlying disease, and incompleteness of collected data. Management recommendations are based on relatively low levels of evidence, and there is some variation between society guideline recommendations. This article seeks to review the available evidence regarding pregnancy-related aortic dissection in women inherited syndromic aortopathies, highlighting the importance of pre-conception counselling, genetic testing and a multi-disciplinary team approach to management.

Indexed as

aortic dissectionbicuspid aortic valveinherited aortopathyLoeys-DietzMarfan'spre-conception counsellingPregnancyTurner's

Identifiers

PMID40687619
PMCPMC12274210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.