Evidence map›Paper›PMID 40687467›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2025

Nomogram for the Therapeutic Efficacy of Apheresis Platelet Transfusion in Hematologic Patients.

Yiwen He, Huihui Feng, Lu Yu, Gang Deng

Abstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yiwen HeDepartment of Blood Transfusion, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010 China.ORCID 0009-0003-0441-9685
Huihui FengInstitute of Blood Transfusion, Ningbo Blood Center, Ningbo, 315010 China.
Lu YuInstitute of Blood Transfusion, Ningbo Blood Center, Ningbo, 315010 China.
Gang DengInstitute of Blood Transfusion, Ningbo Blood Center, Ningbo, 315010 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore the factors that affect the efficacy of apheresis platelet transfusion in patients with hematologic diseases and construct a nomogram prediction model to predict the possibility of obtaining satisfactory platelet transfusion efficacy and guide scientific and rational platelet transfusion. The basic information of 2,007 hematologic patients who received apheresis platelet transfusions from June 2022 to April 2023 and the corresponding donor information and apheresis platelet data are collected. The risk factors that cause ineffective platelet transfusions are screened through a logistic regression analysis. Then, the risk factors are introduced into R software, and a nomogram prediction model is established and validated. The regression analysis shows that the independent risk factors for ineffective platelet transfusion are platelet count before transfusion, white blood cell count, hemoglobin content and mean corpuscular hemoglobin, cumulative platelet transfusion times, platelet antibody positivity, fever, splenomegaly, graft-versus-host disease, bleeding, and platelet storage days. These factors are included in the nomogram, and the calibration curve for predicting transfusion efficiency reveals good consistency between the nomogram-predicted results and the actual observations. The area under the curve obtained through internal repeated sampling is 0.756. This study comprehensively assessed the risks associated with factors leading to ineffective platelet transfusion and successfully constructed and validated a nomogram prediction model. This model provides an important predictive tool for assessing the efficacy of platelet transfusion in patients with hematologic diseases, with the potential to guide scientific and rational platelet transfusion practices. Supplementary Information: The online version contains supplementary material available at 10.1007/s12288-024-01857-0.

Indexed as

Hematologic diseasesNomogramPlatelet transfusion refractorinessPrediction model

Identifiers

PMID40687467
PMCPMC12267762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.