Evidence map›Paper›PMID 40687323›Full record

ArticleGastroenterology research2025

Endoscopic Biliary Drainage in Malignant Biliary Strictures: A Prospective Analysis Based on Real-World Data.

Julio Zuniga Cisneros, Alexis Mc-Kenzie, Ivan Ramos, Eric Ortiz, Orlando Quiros, Calixto Duarte-Chang, Carlos Tunon

Abstract read
In one paragraph

Article in Gastroenterology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julio Zuniga CisnerosDepartment of Gastroenterology, Instituto Oncologico de Panama, Panama City, Panama.ORCID https://orcid.org/0000-0002-4659-3468
Alexis Mc-KenzieDepartment of Gastroenterology, Complejo Hospitalario Metropolitano de Panama, Panama City, Panama.
Ivan RamosDepartment of Gastroenterology, Complejo Hospitalario Metropolitano de Panama, Panama City, Panama.
Eric OrtizDepartment of Gastroenterology, Complejo Hospitalario Metropolitano de Panama, Panama City, Panama.
Orlando QuirosDepartment of Gastroenterology, Complejo Hospitalario Metropolitano de Panama, Panama City, Panama.
Calixto Duarte-ChangDepartment of Gastroenterology, Hospital San Miguel Arcangel, Panama City, Panama.
Carlos TunonDepartment of Gastroenterology, Instituto Oncologico de Panama, Panama City, Panama.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic biliary drainage has emerged as the standard treatment for palliative drainage in malignant biliary strictures (MBS). Methods: This prospective study aimed to investigate the outcomes of patients diagnosed with MBS who underwent biliary drainage through endoscopic retrograde cholangiopancreatography (ERCP) at Complejo Hospitalario Metropolitano. The primary goals were to evaluate the stent dysfunction (SD) and mortality over a 12-month follow-up period. We evaluated the technical and functional deployment success rates according to the stricture location and type of stent used. Results: Out of 191 patients screened, 147 were eligible for inclusion. Distal strictures exhibited significantly higher technical (96.3%) and functional (75.8%) success deployment rates compared to hilar strictures (32.4% technical, 58.8% functional). The overall incidence of SD reached 46.9%, while mortality was 43.5%. Notably, complications varied by stricture type, with bacteremia predominating in hilar stricture cases. Conclusion: The findings from our prospective study affirm a commendably high rate of successful endoscopic stenting interventions along with a lower incidence of adverse events in patients suffering from MBS. Conversely, it is imperative to acknowledge that the endoscopic management of malignant hilar strictures necessitates a more individualized approach due to the elevated complication rates and increased likelihood of SD observed in our study.

Indexed as

Biliary strictureCholangiocarcinomaEndoscopic stentingMalignant

Identifiers

PMID40687323
PMCPMC12267079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.