Evidence map›Paper›PMID 40687272›Full record

ArticleAcademia medicine2025

Inflammatory bowel disease patients believe cannabis and cannabidiol oil relieve symptoms.

Ayati Lala, Alexander Rodriguez-Palacios, Fabio Cominelli, Abigail Raffner Basson

Abstract read
In one paragraph

Article in Academia medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayati LalaDepartment of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA.
Alexander Rodriguez-PalaciosDivision of Gastroenterology and Liver Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Fabio CominelliDivision of Gastroenterology and Liver Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Abigail Raffner BassonDivision of Gastroenterology and Liver Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Funding

The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Fabio Cominelli · 2015 to 2026
$15.6M
Effect of an Anti-Inflammatory Diet on Gut Homeostasis in Active and Experimental Crohn's DiseaseK01DK127008 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RAFFNER, ABIGAIL · 2021 to 2025
$610k
NIDDK NIH HHS K01 DK127008NIDDK NIH HHS P30 DK097948
6 · The paper itself

Abstract

Background: Patients with Inflammatory bowel disease (IBD) often seek alternative therapies for symptom management. This study investigates the perceptions, consumption patterns, and reported outcomes of cannabis and cannabidiol (CBD) oil use among IBD patients and controls. Methods: A 37-question survey was administered to 139 participants (IBD patients, Results: Cannabis consumption was higher in IBD patients (57, 53.8%) than controls (15, 45.5%) with both groups strongly supporting medical cannabis use (IBD; 92, 86.8% vs. controls; 29, 84.9%). Most IBD patients believed cannabis (67, 63.2%), CBD oil (60, 56.6%), corticosteroids (77, 73.3%), and biologics/immunosuppressants (85, 81.0%) had a somewhat-extremely beneficial effect in relieving IBD symptoms. Over 50% of IBD cannabis users reported relief from abdominal pain, other pain, stress, anxiety, depression, and nausea/vomiting, with Crohn's disease patients experiencing significantly more relief than ulcerative colitis patients for certain symptoms ( Conclusions: Consumption of cannabis and CBD oil was perceived as beneficial for relieving IBD, with many reporting significant symptom relief from using these substances. The strong support of cannabis and CBD oil as medical treatments and therapeutic effects highlights the potential for cannabis and CBD oil as treatments in IBD.

Indexed as

cannabidiol oilcannabisCrohn’s diseaseinflammatory bowel diseaseulcerative colitis

Identifiers

PMID40687272
PMCPMC12276967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.