Evidence map›Paper›PMID 40687177›Full record

ReviewJournal of Alzheimer's disease reports

Insulin resistance and Alzheimer's disease: Exploring research hotspots and frontiers from a bibliometric and visual analysis (2005-2024).

Yabin Zhang, Yuting Lv, Tiantian Yang, Qianqian Liu, Qi Guo

Abstract readReview
In one paragraph

Review in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yabin ZhangDepartment of Special Services, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China.
Yuting LvCampus Clinic, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Tiantian YangDepartment of Traditional Chinese Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Qianqian LiuDepartment of Traditional Chinese Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Qi GuoDepartment of Special Services, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong, China.ORCID https://orcid.org/0000-0001-7542-9539

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alzheimer's disease (AD) and insulin resistance (IR) share intersecting pathological pathways, with IR increasingly implicated in AD pathogenesis. Systematic bibliometric analyses mapping the evolution of this interdisciplinary field remain limited. Objective: To quantify global research trends, collaboration networks, knowledge structures, and emerging frontiers in IR-AD research from 2005-2024. Methods: We analyzed 2676 publications from the Web of Science Core Collection. Using VOSviewer, CiteSpace, and bibliometrix R package, we conducted quantitative analyses and visualized multiple dimensions including annual publications/citations, countries/regions, institutions, journals, authors, references, and keywords. Results: Annual publications grew steadily, peaking at 267 in 2022. The United States dominated productivity (942 papers, 35.2%) and citations (88,170). The University of Kentucky was the top institution (53 papers), while the Conclusions: These findings underscore IR-AD as a critical intersection of metabolic and neurodegenerative pathways, advocating for targeted therapies addressing neuroinflammation and cerebral metabolism. By delineating global trends, this study provides a roadmap for future research to bridge translational gaps in AD pathogenesis and treatment.

Indexed as

Alzheimer's diseasebibliometricbibliometrix RCiteSpaceinsulin resistanceVOSviewer

Identifiers

PMID40687177
PMCPMC12276435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.