Evidence map›Paper›PMID 40687165›Full record

ArticleThe Pan African medical journal2025

Unusual clinical presentations in an aquaporin-4 antibody-positive patient: a case report.

Hajar Oualmam, Mohamed Chraa, Nissrine Louhab, Najib Kissani

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hajar OualmamNeuroscience Research Laboratory of Marrakech Medical School, Cadi Ayyad University, Marrakech, Morocco.
Mohamed ChraaNeuroscience Research Laboratory of Marrakech Medical School, Cadi Ayyad University, Marrakech, Morocco.
Nissrine LouhabNeuroscience Research Laboratory of Marrakech Medical School, Cadi Ayyad University, Marrakech, Morocco.
Najib KissaniNeuroscience Research Laboratory of Marrakech Medical School, Cadi Ayyad University, Marrakech, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune condition affecting the central nervous system, primarily targeting the optic nerves and spinal cord. We report the case of a 52-year-old patient with no significant medical history who presented with bilateral lower limb heaviness and sensory disturbances. Neurological examination revealed peripheral neurogenic syndrome and syringomyelic dissociation. The presence of anti-aquaporin 4 (AQP4) antibodies confirmed the diagnosis of NMOSD. Treatment with corticosteroids and immunosuppressants led to clinical improvement. This case highlights the need for heightened clinical suspicion in patients with atypical neurological symptoms, as NMOSD can present beyond its classical opticospinal manifestations, ensuring timely diagnosis and appropriate management.

Indexed as

Aquaporin 4AutoantibodiesNeuromyelitis OpticaAdrenal Cortex HormonesHumansImmunosuppressive AgentsMiddle AgedAdrenal Cortex HormonesAQP4 protein, humanAquaporin 4AutoantibodiesImmunosuppressive Agentsaquaporin-4 antibodiescase reportcentral nervous systemNeuromyelitis optica

Identifiers

PMID40687165
PMCPMC12274387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.