ReviewJournal of inflammation research2025
Alterations in Signaling Pathways and Therapeutic Strategies of Traditional Chinese Medicine in Granulomatous Lobular Mastitis.
Review in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Different forms of cardiomyocyte death in post-myocardial infarction ventricular remodeling: mechanisms and therapeutic strategies.Frontiers in cardiovascular medicine · 2026Review
- Tuoli Tounong decoction promotes lesion resolution in granulomatous lobular mastitis by remodeling a Caspase-8-associated PANoptosis-like cell death network.Frontiers in immunology · 2026Article
- Granulomatous mastitis: from localized inflammation to systemic immune-mediated disorder.Frontiers in medicine · 2026Review
- Integrated Transcriptomics and Network Pharmacology Reveal the Mechanism of Poplar-Type Propolis on the Mouse Mastitis Model.Nutrients · 2025Article
- Traditional Chinese medicine and plant-derived bioactive compounds as sustainable alternatives to antibiotics in bovine mastitis: a review.Frontiers in veterinary science · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Granulomatous lobular mastitis (GLM), a clinically challenging inflammatory breast disease, is characterized by a high recurrence rate, strong invasiveness, and a trend of affecting younger individuals, posing significant challenges to patients and clinical practitioners. Its pathological processes involve the abnormal activation of multiple signaling pathways, including NF-κB, NLRP3, JAK/STAT, TLR, MAPK, PI3K/AKT/mTOR, and Nrf2/HO-1. These pathways contribute to the disease's onset and progression by regulating inflammatory responses, immune reactions, and oxidative stress. Traditional Chinese Medicine (TCM) demonstrates unique therapeutic value in the treatment of GLM by virtue of its multi-component and multi-target mechanisms. Through modulation of the aforementioned signaling pathways, TCM can effectively inhibit inflammatory cascades, regulate immune imbalance, and ameliorate oxidative stress, thereby reducing lesion size, shortening disease course, and lowering recurrence rates. This article systematically reviews the research progress on GLM-related signaling pathways and integrates the latest evidence on the interventional mechanisms of Chinese medicine, aiming to provide new insights for precision clinical treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.