ReviewClinical neurophysiology practice2025
Triphasic waves: To treat or not to treat?
Review in Clinical neurophysiology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Perioperative assessment of electroencephalography in dogs with congenital portosystemic shunts.Journal of veterinary internal medicine · 2026Article
- Response to "Triphasic waves: To treat or not to treat?": Do not overlook COVID-19 and Creutzfeldt-Jakob disease.Clinical neurophysiology practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Generalized periodic discharges (GPDs) with triphasic morphology (triphasic waves, TWs) are EEG waveforms that have been a frequent topic of research evaluating their etiology and clinical correlates. More specifically, prior studies have tried to better elucidate their implications regarding seizures to help guide decision making regarding empiric treatment and EEG monitoring and in spite of multiple studies, controversies remain due to disparate findings. In this review we discuss the historical views of TWs and their clinical and radiographic correlates, highlight the typical and atypical features of TWs, discuss the controversy related to the association between TWs and seizures, and propose an approach to their management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.