Evidence map›Paper›PMID 40686766›Full record

ArticleAmerican journal of ophthalmology case reports2025

Preserflo™ microshunt for the treatment of refractory childhood glaucoma: A case series study.

Yuri Tanaka, Shiho Kasahara, Ryo Tomita, Norie Nonobe, Kazuhide Kawase, Kenya Yuki

Abstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuri TanakaDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, 65, Tsurumai, Syowa Ward, Nagoya, Aichi, 466-8560, Japan.
Shiho KasaharaDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, 65, Tsurumai, Syowa Ward, Nagoya, Aichi, 466-8560, Japan.
Ryo TomitaDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, 65, Tsurumai, Syowa Ward, Nagoya, Aichi, 466-8560, Japan.
Norie NonobeIto Eye Clinic, 25-1, Gonaka, Azaicho, Nishiazai, Ichinomiya, Aichi, 491-0113, Japan.
Kazuhide KawaseDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, 65, Tsurumai, Syowa Ward, Nagoya, Aichi, 466-8560, Japan.
Kenya YukiDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, 65, Tsurumai, Syowa Ward, Nagoya, Aichi, 466-8560, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We report the outcomes of five patients with pediatric glaucoma, who were treated with Preserflo™ microshunt surgery. Methods: This prospective study included five consecutive patients who underwent Preserflo™ microshunt surgery at the Nagoya University Hospital. The main outcome measures evaluated in this study were mean intraocular pressure (IOP), number of glaucoma medications, and best corrected visual acuity (BCVA). Paired t-tests with Bonferroni correction were used to compare the baseline and follow-up periods, where p < 0.05 was considered statistically significant. Results: Average age at the time of surgery was 10 ± 4 years. Three patients had primary congenital glaucoma, one had Sturge-Weber syndrome, and one had juvenile open-angle glaucoma. Preoperative average IOP was 37.6 ± 4.7 mmHg. After microshunt surgery, IOP significantly decreased to 6.3 ± 1.2 mmHg in 1 day, 6.6 ± 1.7 mmHg in 1 week, 9.6 ± 6.1 mmHg in 1 month, 12.0 ± 7.4 mmHg in 3 months, 10.0 ± 5.2 mmHg in 6 months, 14.2 ± 8.7 mmHg in 9 months, and 10.5 ± 6.5 mmHg in 1 year (p < 0.01 for each paired Conclusion: Microshunt surgery may be a useful option for treating glaucoma in pediatric patients, in whom trabeculotomy failed.

Indexed as

Anti-glaucoma medicationsChildhood glaucomaIntraocular pressurePreserflo™ microshuntTrabeculotomy

Identifiers

PMID40686766
PMCPMC12274881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.