ArticleTurkish journal of medical sciences2025
Short-term efficacy and safety of nondamaging retinal laser therapy for retinitis pigmentosa-associated cystoid macular edema.
Article in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Management of full-thickness macular holes in patients with retinitis pigmentosa - a case series of 5 patients operated with pars plana vitrectomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
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Authors and funding
4 authors.
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Abstract
Background/aim: To evaluate the short-term efficacy and safety of nondamaging retinal laser therapy (NRT) for retinitis pigmentosa-associated cystoid macular edema (RP-CME) and analyze anatomical and functional outcomes. Materials and methods: A retrospective case series of 40 eyes from 30 patients with RP-CME was conducted. The patients underwent NRT using a PASCAL laser system with endpoint management (EpM) software. Central macular thickness (CMT) and best-corrected visual acuity (BCVA) were assessed at baseline and 2 months posttreatment. Long-term follow-up data, including recurrence rates were also reviewed. Results: At the 2-month follow-up, NRT significantly reduced mean CMT by 79.7 μm (p < 0.001) and improved BCVA by 0.10 LogMAR (p < 0.001). Complete resolution of CME was observed in 30% of the eyes, while 52.5% experienced recurrence within 6 months. Unilateral cases exhibited greater CMT reductions than bilateral cases (p < 0.05). No retinal damage from the laser was observed. The long-term sustainability of these effects remains unclear, and repeated treatments have not yet been assessed. Conclusion: NRT is a safe and effective short-term treatment for RP-CME, achieving significant anatomical and functional improvements without evidence of retinal damage. However, the high recurrence rate and absence of long-term data warrant further investigation. Future studies should explore repeated treatments, genetic subtypes, and correlations with the ellipsoid zone integrity.
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