Trial reportTurkish journal of medical sciences2025
Effectiveness of ultrasonography-guided periforaminal oxygen-ozone therapy in chronic low back pain.
Trial report in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Subacute and Chronic Low-Back Pain: From MRI Phenotype to Imaging-Guided Interventions.Diagnostics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: Treatment of chronic low back pain (LBP) includes various minimally invasive image-guided interventional techniques. The aim of this study, which was planned based on the idea that periforaminal oxygen-ozone (O2-O3) gas application with ultrasonography (USG) could be an alternative treatment option, was to compare the therapeutic efficacy of USG-guided periforaminal ozone infiltration (PFOI) or transforaminal epidural steroid injection (TFESI) in patients with chronic radicular LBP on pain, disability, and quality of life (QoL). Materials and methods: A total of 50 patients were randomly divided into 2 groups of 25 patients each underwent PFOI by USG or TFESI via fluoroscopy. Pain intensity was assessed with visual analogue score (VAS), disability with Oswestry disability index (ODI), and QoL with short form-36 (SF-36), before treatment, at the 2nd week, 1st month, and 2nd month, after treatment. Results: Intra-group comparisons showed significant improvements in LBP VAS, radicular pain VAS, and ODI after treatment for both groups. The reduction in LBP VAS was found to be higher in the PFOI group at week 2 (p = 0.010) and month 1 (p = 0.037), and the improvement in ODI scores was significantly better in the PFOI group at week 2 (p = 0.017) compared to the TFESI group. Conclusion: Our findings have shown that PFOI and TFESI have positive effects on chronic radicular LBP, disability, and QoL parameters. Since ultrasound-guided O2-O3 injections were found to be more effective than epidural steroid injections, particularly in the early period, it was suggested that O2-O3 therapy may be considered in the preoperative treatment algorithm of patients with chronic radicular LBP.
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Registered trials
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