Evidence map›Paper›PMID 40686695›Full record

ArticleTurkish journal of medical sciences2025

Investigation of the relationship between the triglyceride-glucose index and metabolic and hematological parameters in obese individuals.

Özge Baş Aksu, Feride Özkara, Rıfat Emral, Volkan Genç, Demet Çorapçioğlu, Mustafa Şahin

Abstract read
In one paragraph

Article in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Özge Baş AksuDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0003-3124-9477
Feride ÖzkaraDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0001-7255-9995
Rıfat EmralDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0002-5732-2284
Volkan GençDepartment of General Surgery, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0003-3883-4791
Demet ÇorapçioğluDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0003-0940-9147
Mustafa ŞahinDepartment of Endocrinology and Metabolism, Faculty of Medicine, Ankara University, Ankara, Turkiye.ORCID https://orcid.org/0000-0002-4718-0083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: This research examined the association between the triglyceride-glucose (TyG) index and metabolic, hepatic, and hematologic variables in a population of severely obese subjects, with a focus on the assessment of glycemic control. Materials and methods: This retrospective study included 315 adult patients with a body mass index (BMI) ≥ 35 kg/m Results: Individuals with HbA1c ≥ 6.5% had significantly higher TyG, AIP, APRI, and FIB-4 values than those with lower HbA1c. The TyG index showed a strong correlation with both HbA1c (r = 0.403, p < 0.001) and AIP (r = 0.866, p < 0.001), and was identified as an independent predictor of HbA1c, explaining 20.5% of its variance. Moderate correlations were also found between liver fibrosis scores and systemic inflammatory indices. No significant differences were observed in hematologic markers across HbA1c groups, suggesting a closer link between inflammation and obesity rather than glycemic status. Conclusion: The TyG index may serve as a practical and accessible marker for metabolic risk and glycemic control in obese individuals. Its integration with other noninvasive indices like AIP, APRI, and FIB-4 may support a more comprehensive evaluation of cardiometabolic and hepatic risk profiles in clinical settings.

Indexed as

Blood GlucoseObesityTriglyceridesAdultBiomarkersBody Mass IndexFemaleGlycated HemoglobinHumansMaleMiddle AgedRetrospective StudiesBiomarkersBlood GlucoseGlycated HemoglobinTriglyceridesAIPdiabetes mellitusFIB4ObesityTyG index

Identifiers

PMID40686695
PMCPMC12270320

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.