Evidence map›Paper›PMID 40686655›Full record

ArticleJVS-vascular science2025

Three-dimensional characterization of ascending aortic strain, motion and growth in patients undergoing thoracic endovascular aortic repair.

Nicasius Tjahjadi, Carlos Campello Jorge, Prabhvir S Marway, Taeouk Kim, Timothy Baker, Constantijn Hazenberg, Joost A van Herwaarden, C Alberto Figueroa, Himanshu J Patel, Nicholas S Burris

Abstract read
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In one paragraph

Article in JVS-vascular science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicasius TjahjadiDepartment of Cardiac Surgery, University of Michigan Hospitals, Ann Arbor, MI.
Carlos Campello JorgeDepartment of Radiology, University of Michigan Hospitals, Ann Arbor, MI.
Prabhvir S MarwayDepartment of Radiology, University of Michigan Hospitals, Ann Arbor, MI.
Taeouk KimDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI.
Timothy BakerDepartment of Radiology, University of Michigan Hospitals, Ann Arbor, MI.
Constantijn HazenbergDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Joost A van HerwaardenDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
C Alberto FigueroaDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI.
Himanshu J PatelDepartment of Cardiac Surgery, University of Michigan Hospitals, Ann Arbor, MI.
Nicholas S BurrisDepartment of Radiology, University of Michigan Hospitals, Ann Arbor, MI.

Funding

Non-invasive hemodynamic and biomechanic imaging methods for early risk prediction in aortic dissectionR01HL170059 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Nicholas Scott Burris, David Alexander Nordsletten · 2023 to 2026
$2.4M
NHLBI NIH HHS R01 HL170059
6 · The paper itself

Abstract

Objective: We utilized vascular deformation mapping (VDM) to assess ascending aortic motion, regional stiffness and growth in patients who underwent zone 2/3 thoracic endovascular aortic repair (TEVAR) to quantify changes in ascending aorta biomechanics after endograft implantation. Methods: Multi-planar, multi-directional aortic motion, aortic strain, and three-dimensional aortic growth was extracted by VDM from electrocardiography-gated computed tomography angiograms. Aortic displacement and strain were compared between patients who underwent TEVAR (both pre- and post-procedure) and in patients with dilated ascending aorta (>4.0 cm) and a non-dilated control group. Results: One hundred twenty subjects were included for analysis. Between pre-TEVAR and post-TEVAR, total displacement decreased (4.87 ± 1.52 mm vs 4.13 ± 1.43 mm; Conclusions: Zone 2/3 TEVAR introduces changes in ascending aortic biomechanics. Patients with lower post-TEVAR strain, suggesting higher aortic stiffness, may be at highest risk of progressive growth. Imaging-based assessment of aortic biomechanics may help improve risk stratification for long-term outcomes post-TEVAR.

Indexed as

Aortic motionAortic stiffnessComputed tomography angiographyThoracic aortic aneurysmThoracic endovascular aortic repairVascular deformation mapping

Identifiers

PMID40686655
PMCPMC12272903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.