Evidence map›Paper›PMID 40686635›Full record

ArticleRSC advances2025

Eradication of MRSA biofilms using amphiphilic cationic coumarin derivatives.

Samuel O Nitschke, Muhammed Awad, Alysha G Elliott, Gabrielle Lowe, Chris Leigh, Ken Neubauer, Nicky Thomas, Shane M Hickey, Sally E Plush

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Defining a lipophilicity window for the antimicrobial activity of 7-Alkoxy-3-Amino coumarin amphiphiles.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  2. Potential of Fermented Food-DerivedInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samuel O NitschkeClinical and Health Sciences, University of South Australia Adelaide South Australia 5000 Australia sally.plush@unisa.edu.au.ORCID https://orcid.org/0000-0002-4455-2056
Muhammed AwadClinical and Health Sciences, University of South Australia Adelaide South Australia 5000 Australia sally.plush@unisa.edu.au.
Alysha G ElliottInstitute for Molecular Bioscience, The University of Queensland Brisbane Queensland 4072 Australia.
Gabrielle LoweInstitute for Molecular Bioscience, The University of Queensland Brisbane Queensland 4072 Australia.
Chris LeighAdelaide Microscopy, The University of Adelaide Adelaide South Australia 5000 Australia.
Ken NeubauerAdelaide Microscopy, The University of Adelaide Adelaide South Australia 5000 Australia.
Nicky ThomasClinical and Health Sciences, University of South Australia Adelaide South Australia 5000 Australia sally.plush@unisa.edu.au.
Shane M HickeyClinical and Health Sciences, University of South Australia Adelaide South Australia 5000 Australia sally.plush@unisa.edu.au.ORCID https://orcid.org/0000-0002-3063-531X
Sally E PlushClinical and Health Sciences, University of South Australia Adelaide South Australia 5000 Australia sally.plush@unisa.edu.au.ORCID https://orcid.org/0000-0002-9999-9154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphiphilic coumarin derivatives have demonstrated potent antibiofilm activity against established methicillin-resistant

Identifiers

PMID40686635
PMCPMC12272568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.