Evidence map›Paper›PMID 40686520›Full record

ArticleBreast cancer (Dove Medical Press)2025

A Machine-Learning Model for the Prediction of Triple-Negative Breast Cancer Based on Multiparameter MRI.

Yuxin Cai, Yanbo Li, Wenqi Wang, Yaqiu Zhou, Jingbo Wang, Lina Zhang, Hong Lu

Abstract read
In one paragraph

Article in Breast cancer (Dove Medical Press), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuxin Cai *Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Yanbo Li *Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Wenqi WangDepartment of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Yaqiu ZhouDepartment of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Jingbo WangDepartment of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Lina ZhangDepartment of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.
Hong LuDepartment of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People's Republic of China.ORCID 0000-0002-1004-1792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the difference between triple-negative breast cancer (TNBC) and non-triple-negative breast cancer (non-TNBC) based on multi-parametric MRI imaging features and construct a prediction model to identify TNBC. Methods: A retrospective study enrolled 1353 women with 1376 malignant lesions who had no additional therapy before surgery between January 2019 and December 2020 in a single center. The images were accessed according to BI-RADS-MR Results: Necrosis, edema, the maximum diameter of lesions, enhancement ratio in each phase, time to peak, gland enhancement ratio, wash-in slope and the number and diameter of the vessels were independent predictors predicting TNBC. The AUCs of the model were 0.795 (95% CI: 0.758-0.832) and 0.705 (95% CI: 0.640-0.770) in the primary cohort and validation cohort, respectively. Conclusion: The model based on multiparameter MRI has good predictive ability and can be used to predict the probability of TNBC.

Indexed as

magnetic resonance imagingmodelsemi-quantitative parameterstriple negative breast cancervessel

Identifiers

PMID40686520
PMCPMC12275995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.