SynthesisDiagnostic and interventional radiology (Ankara, Turkey)2025
Diagnostic performance of magnetic resonance imaging for lateral pelvic lymph node metastasis in patients with rectal carcinoma: a meta-analysis and systematic review.
Synthesis in Diagnostic and interventional radiology (Ankara, Turkey), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Lateral pelvic lymph nodes in rectal cancer: a narrative review.Abdominal radiology (New York) · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAccurate identification of lateral pelvic lymph node (LPLN) metastasis is imperative for guiding LPLN dissection to reduce local recurrence in patients with rectal carcinoma. This meta-analysis aimed to investigate the diagnostic performance of magnetic resonance imaging (MRI) for LPLN metastasis in patients with rectal carcinoma.
methodsEmbase, PubMed, Web of Science, and the Cochrane Library were searched to identify studies related to the diagnostic performance of MRI for LPLN metastasis in patients with rectal carcinoma through June 2024.
resultsThis meta-analysis included 12 studies comprising 1,015 patients. The pooled sensitivity [95% confidence interval (CI)] and specificity (95% CI) of MRI for diagnosing LPLN metastasis were 0.66 (0.53, 0.80) and 0.82 (0.76, 0.88), respectively. The pooled positive likelihood ratio (LR) (95% CI) and negative LR (95% CI) were 2.82 (2.14, 3.51) and 0.41 (0.27, 0.55), respectively. The summary receiver operating characteristic curve indicated an area under the curve of 0.824. The quality of the included studies was acceptable according to the Quality Assessment of Diagnostic Accuracy Studies-2 tool. However, publication bias was present, as indicated by Deeks' funnel plot asymmetry test (
conclusionPreoperative MRI demonstrates an acceptable ability to identify LPLN metastasis in patients with rectal carcinoma. CLINICAL SIGNIFICANCE: Clinically, our findings support that preoperative MRI has acceptable diagnostic ability for LPLN metastasis in patients with rectal carcinoma. The preoperative application of MRI may aid in optimizing treatment strategies and improving prognosis in this population.
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