Observational studyInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026
Clinical differences between adipose- and muscle-layer cesarean scar endometriosis: A retrospective observational study.
Observational study in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Clinical differences between adipose- and muscle-layer cesarean scar endometriosis: A retrospective observational study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
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4 authors.
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Abstract
BACKGROUND/
aimThis study evaluated cesarean section scar endometriosis (CSSE) characteristics and compared adipose- and muscle-layer CSSEs. MATERIALS AND
methodsWe analyzed 53 patients who underwent CSSE surgery between 2019-2024, with 38 (71.7%) having adipose-layer and 15 (28.3%) having muscle-layer CSSE.
resultsPatients' mean age was 33.4 ± 5.9 years. Symptoms began 40.4 ± 23.5 months after cesarean section. CSSE occurred at scar corners in 42 patients (79.2%) and midline in 11 (20.8%). Mean preoperative CA-125 was 24.1 ± 14.8 U/mL. Groups differed in symptoms, location, and CA-125 levels. Adipose-layer CSSE commonly presented with swelling at corners, while muscle-layer CSSE showed pain at midline. Muscle-layer CSSE had higher CA-125 levels (38.2 ± 19.2 vs. 18.5 ± 7.3 U/mL; P = 0.01). The CA-125 cutoff between groups was 30 U/mL. Pain (odds ratio [OR], 7.2; P = 0.03) and elevated CA-125 (≥30 U/mL) (OR, 19.6; P < 0.01) independently associated with muscle-layer CSSE.
conclusionThese findings may have important implications in clinical practice, potentially aiding in the localization of undefined lesions, surgical planning, and monitoring of recurrence risk.
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