Evidence map›Paper›PMID 40686316›Full record

ArticleThe Journal of organic chemistry2025

Methyl Radical Addition Reactions to C═X Double Bonds.

Yuman Hordijk, Bart Waaijer, Christopher B Kelly, Trevor A Hamlin

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Methyl Radical Addition Reactions to C═X Double Bonds.The Journal of organic chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuman HordijkDepartment of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands.ORCID 0000-0002-0777-4274
Bart WaaijerDepartment of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands.
Christopher B KellyDiscovery Process Research, Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania 19477, United States.ORCID 0000-0002-5530-8606
Trevor A HamlinDepartment of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands.ORCID 0000-0002-5128-1004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical additions to olefins and related π-systems are essential tools in the modern synthetic toolbox for forging C-C and C-X bonds. We report a systematic DFT study (ZORA-(U)OLYP/TZ2P) on methyl radical (H

Identifiers

PMID40686316
PMCPMC12322914

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.