Trial reportJournal of oral rehabilitation2025
Risk and Health Factors for Temporomandibular Disorders Following Radiotherapy for Head and Neck Cancer.
Trial report in Journal of oral rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The indirect effect of temporomandibular kinesiophobia on the association between limited mouth opening symptoms and maximum mouth opening in postoperative oral cancer patients: a mediation analysis.Clinical oral investigations · 2026Article
- Imaging findings in the temporomandibular joint complex following radiation therapy for head and neck cancer: a review.Insights into imaging · 2026Review
- Radiation-induced oral side effects in head and neck cancer: a scoping review and interdisciplinary recommendations.BMC oral health · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundTemporomandibular disorders (TMD) are multifactorial and complex musculoskeletal conditions frequently associated with pain or dysfunction, including impaired jaw function and pain in the temporomandibular joint, masticatory muscles and/or related structures. Recent studies have found that personality, behaviour and environment can affect the development of TMD.
objectiveThis study investigates whether patient-related factors can predict TMD among patients with head and neck cancer (HNC) after radiotherapy.
methodsWe randomised 58 consecutive patients with squamous cell carcinoma in the head and neck area into two groups: training with a jaw mobiliser once a day or a control group (no training). A comprehensive examination for TMD was conducted at baseline (before oncologic treatment) and 6 and 12 months after radiotherapy. Potential predictors were analysed using linear and logistic regression analyses.
resultsMyalgia was associated with TMD diagnosis at baseline, and jaw exercise lowered the risk of developing myalgia at the follow-ups. The degree of pain at baseline and jaw exercise were associated with the changes in pain at follow-ups. Jaw exercise was associated with a lower degree of pain. A high degree of pain at baseline was associated with less pain at follow-ups. Jaw exercise was associated with a reduced risk of decreased maximal incisal mouth opening post treatment.
conclusionNo psychosocial or other background factor reduced risk for myalgic pain or pain to the same degree as jaw exercise. Therefore, we recommend using jaw training to prevent the deterioration of maximal incisal opening and the development of pain associated with TMD.
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