Evidence map›Paper›PMID 40685976›Full record

ArticleJournal of cellular physiology2025

Notum as a Crucial Regulator of Matrix Integrity in Dentinogenesis.

Hwajung Choi, Ju-Kyung Jeong, Dinuka Adasooriya, Sung-Won Cho, Eui-Sic Cho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hwajung ChoiCluster for Craniofacial Development and Regeneration Research, Institute of Oral Bioscience, Jeonbuk National University School of Dentistry, Jeonju, Republic of Korea.
Ju-Kyung JeongCluster for Craniofacial Development and Regeneration Research, Institute of Oral Bioscience, Jeonbuk National University School of Dentistry, Jeonju, Republic of Korea.
Dinuka AdasooriyaDivision of Anatomy and Developmental Biology, Department of Oral Biology, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.ORCID 0000-0002-8413-8247
Sung-Won ChoDivision of Anatomy and Developmental Biology, Department of Oral Biology, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Eui-Sic ChoCluster for Craniofacial Development and Regeneration Research, Institute of Oral Bioscience, Jeonbuk National University School of Dentistry, Jeonju, Republic of Korea.ORCID 0000-0002-7389-9817

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dentinogenesis, the formation of dentin, requires precise coordination of cellular differentiation, extracellular matrix synthesis, and signaling regulation. Here, we elucidate the role of Notum, a secreted Wnt inhibitor, in orchestrating these processes during dentin formation. In Notum

Indexed as

DentinDentinogenesisExtracellular MatrixAnimalsbeta CateninCell DifferentiationDental PulpDentin SialophosphoproteinExtracellular Matrix ProteinsMiceMice, KnockoutOdontoblastsOdontogenesisPhosphoproteinsSialoglycoproteinsWnt Signaling Pathwaybeta CateninDentin SialophosphoproteinExtracellular Matrix ProteinsPhosphoproteinsSialoglycoproteinsdentinogenesisextracellular matrixNotumodontoblastsWnt/β‐catenin signaling

Identifiers

PMID40685976
PMCPMC12277939

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.