Evidence map›Paper›PMID 40685737›Full record

ReviewCurrent neuropharmacology2026

Gut Microbiota and Bipolar Disorder: Advances in Translational Applications.

Liujiao Yan, Shaoxia Zhang, Xiaobing Lu, Zezhi Li

Abstract readReview
In one paragraph

Review in Current neuropharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liujiao YanDepartment of Nutritional and Metabolic Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Shaoxia ZhangDepartment of Psychiatry, Dongguan Seventh People's Hospital, Dongguan, China.
Xiaobing LuDepartment of Nutritional and Metabolic Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Zezhi LiDepartment of Nutritional and Metabolic Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.

Funding

Guangzhou High-level Clinical Key Specialty, and Guangzhou Research-oriented Hospital, The Beijing Kangmeng Charity Foundation 20190121Guangzhou Key R&D Program Agriculture and Social Development Science and Technology Project 202206010034, 202206010077Guangzhou Municipal Key Discipline in Medicine 2021-2023Guangzhou Municiple Health Commission 2023C-TS26National Innovation and Entrepreneurship Training Program for College Students 202410570049Natural Science Foundation of Guangdong Province 2023A1515011728, 2025A1515010816Plan on enhancing scientific research in GMU 02-410-230221XM, GMUCR202402025, GMUCR2025-02027Project of Guangzhou Municipal Science and Technology Bureau 2023A03J0835, 2024A03J0294Tertiary Education Scientific research project of Guangzhou Municipal Education Bureau 202234641
6 · The paper itself

Abstract

Bipolar disorder is a severe, recurrent affective disorder that imposes significant pain and burden on both the patients themselves and the social economy. Recent studies have indicated the involvement of intestinal flora in emotional regulation, as well as its close association with the occurrence and progression of diseases such as bipolar disorder. Therefore, conducting comprehensive research on the impact of intestinal microflora and the "gut-brain axis" on bipolar disorder becomes imperative, offering novel insights into its etiology, diagnosis, and treatment options. Consequently, this article provides an overview of the role and potential mechanisms underlying intestinal microbiota in bipolar disorder.

Indexed as

Bipolar DisorderGastrointestinal MicrobiomeAnimalsBrainHumansTranslational Research, BiomedicalBipolar disorderemotional regulationgut-brain axisgut microbiotaintestinal floraprobiotic

Identifiers

PMID40685737
PMCPMC13270089

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.