Evidence map›Paper›PMID 40685558›Full record

ArticleJournal of feline medicine and surgery2025

Standardized classification of synchronous gastrointestinal small cell lymphoma and gastrointestinal mast cell tumors in 15 cats.

Ann E Hohenhaus, Danielle Hudak, Taryn A Donovan, Christof A Bertram, Heather Daverio

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ann E HohenhausCancer Institute, Schwarzman Animal Medical Center, New York, NY, USA.ORCID 0009-0008-0482-3254
Danielle HudakCancer Institute, Schwarzman Animal Medical Center, New York, NY, USA.
Taryn A DonovanDepartment of Pathology, Schwarzman Animal Medical Center, New York, NY, USA.ORCID 0000-0001-5740-9550
Christof A BertramInstitute of Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.ORCID 0000-0002-2402-9997
Heather DaverioDepartment of Pathology, Schwarzman Animal Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesSynchronous primary tumors have been defined as two or more concurrent, yet independent tumors diagnosed within 6 months or less. The primary objective of this study was to investigate the occurrence and clinical findings in cats with synchronous gastrointestinal (GI) small cell lymphoma (SCL) and GI mast cell tumor (MCT) at two referral hospitals. A secondary objective was to classify these tumors as distinct or mixed, and if mixed, categorize them histomorphologically as collision or combined tumors based on standardized definitions informed by literature review.MethodsThe databases of the Schwarzman Animal Medical Center (AMC) and University of Veterinary Medicine in Vienna, Austria (Vetmeduni) were searched between January 2012 and December 2022 for cats with synchronous GI SCL and GI MCT. Clinical findings, treatment and outcome were abstracted from medical records. Biopsy or autopsy reports and, when available, slides and/or histopathology images indicating the presence of a synchronous GI SCL and GI MCT were reviewed by two board-certified pathologists.ResultsA total of 15 cats were diagnosed with synchronous GI SCL and GI MCT, representing 4.3% of 329 cats with GI SCL in the AMC population. This study identified 15 cats with a total of 18 synchronous tumors. Six cats had tumors classified as distinct tumors and six as combined. Three cats had both distinct and combined tumors. Survival in this group of cats was in the range of 8-1189 days.Conclusions and relevanceThis is the first report to classify synchronous tumors in cats as distinct and combined tumors. The results of this study indicate a wide range of survival times for cats with synchronous GI SCL and GI MCT, suggesting that despite the diagnosis of synchronous tumors, the outcome is similar to cats with either GI SCL or GI MCT.

Indexed as

Cat DiseasesGastrointestinal NeoplasmsNeoplasms, Multiple PrimaryAnimalsCatsFemaleMaleRetrospective Studiescollision tumorcombined tumordistinct tumorgastrointestinal lymphomagastrointestinal mast cell tumorhistopathologymixed tumorSynchronous tumor

Identifiers

PMID40685558
PMCPMC12277675

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.