Evidence map›Paper›PMID 40685409›Full record

ArticleScientific reports2025

Non-invasive quantitative assessment of urethral compliance in rabbit tubularized incised plate model using ultrasound and uroflowmetry.

Hongbo Liu, Wei Ru, Juan Zhou, Ciyuan Feng, Qibo Hu, Guangjie Chen, Weifeng Yang, Lizhe Hu, Xiang Yan

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hongbo Liu *Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Wei Ru *Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Juan ZhouDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Ciyuan FengDepartment of Ultrasound, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Qibo HuDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Guangjie ChenDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Weifeng YangDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Lizhe HuDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China.
Xiang YanDepartment of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Centre for Child Health, Hangzhou, China. yanxiang@zju.edu.cn.

Funding

Zhejiang Province Public Welfare Technology Application Research Project (LGD22H050002) from Science and Technology Department of Zhejiang Province and the National Natural Science Foundation of China No. 82273014
6 · The paper itself

Abstract

Low urinary flow rates are frequently observed following tubularized incised plate urethroplasty. The underlying cause is not yet fully understood and may be associated with low urethral compliance. The purpose of this study is to non-invasively evaluate the urethral compliance in a rabbit model. Ten male New Zealand rabbits were randomly divided into a control group and a urethroplasty group for tubularized incised plate urethroplasty. Seven weeks post-operatively, ex vivo urethral compliance was evaluated using both the Jesus invasive measurement and the non-invasive method. The Jesus measurement involved measuring urethral volume and pressure by air insufflation, and the non-invasive method utilized ultrasound and uroflowmetry to assess the urethral anterior-posterior diameter and flow data, respectively. Curve regression analysis was applied to calculate urethral compliance. Curve regression analysis revealed that the median urethral compliance measured by non-invasive method in the control group was 0.247 (0.241, 0.257) mm•s/ml, and it was 0.269 (0.263, 0.270) mm•s/ml in the urethroplasty group, with no significant difference between the two groups. The Jesus method indicated median urethral compliance was 0.141 (0.137, 0.149) ml/cmH

Indexed as

UrethraAnimalsComplianceMaleRabbitsRheologyUltrasonographyUrodynamicsComplianceHypospadiasUltrasonographyUrethraUroflowmetry

Identifiers

PMID40685409
PMCPMC12277407

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