Evidence map›Paper›PMID 40685163›Full record

ArticleBMJ health & care informatics2025

Proactive process evaluation of precision medicine platforms: a roadmap.

Kathrin Cresswell

Abstract read
In one paragraph

Article in BMJ health & care informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kathrin CresswellUsher Institute, The University of Edinburgh, College of Medicine and Veterinary Medicine, Edinburgh, UK Kathrin.Cresswell@ed.ac.uk.ORCID http://orcid.org/0000-0001-6634-9537

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrecision and genomic medicine have significant potential to improve population health. However, despite rapid technological development and increasing data complexity, practical applications of precision medicine remain limited. There is also a lack of evaluation of unintended consequences and a failure to use theory-based implementation frameworks to manage risks and ensure sustainability.

methodsThis work provides a conceptual overview of evaluation challenges related to precision medicine platforms, based on existing literature. It proposes a theory-informed proactive process evaluation framework to guide the development and assessment of these platforms.

resultsThe proposed framework considers infrastructural, socio-organisational and system-level factors. It raises key questions, such as: How will platforms integrate with existing infrastructures? How will they transform care pathways and the delivery of care across settings?

conclusionsRapid technological advances challenge markets and regulatory environments. Agile evaluation approaches are crucial for building a sustainable innovation ecosystem for precision medicine platforms.

Indexed as

Precision MedicineProcess Assessment, Health CareGenomicsHumansArtificial intelligenceData ScienceHealth Information SystemsHealth Services Research

Identifiers

PMID40685163
PMCPMC12278136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.