Evidence map›Paper›PMID 40684180›Full record

Trial reportJournal of neuroengineering and rehabilitation2025

Repetitive transcranial magnetic stimulation influences cognitive-motor dual-task performance in children with cerebral palsy: a randomized controlled study.

Jingyi Zhao, Tingting Peng, Liru Liu, Lu He, Jingbo Zhang, Yuan Zhang, Qingfen Hou, Hongyu Zhou, Xubo Yang, Kaishou Xu

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jingyi Zhao *Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Tingting Peng *Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Liru Liu *Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Lu He *Department of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Jingbo ZhangDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Yuan ZhangDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Qingfen HouDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Hongyu ZhouDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Xubo YangDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Kaishou XuDepartment of Rehabilitation, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, 510120, China. xksyi@126.com.ORCID http://orcid.org/0000-0002-0639-3488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with cerebral palsy (CP) may face challenges when engaging in activities that require simultaneous cognitive and motor efforts. Repetitive transcranial magnetic stimulation (rTMS) has the potential to improve motor and cognitive functions in some populations. However, the effect of rTMS on the performance of cognitive-motor dual-task in children with CP remains unclear.

objectiveTo investigate the efficacy and safety of rTMS on the performance of cognitive-motor dual-task in children with CP.

methodsIn this randomized controlled trial, forty-four children with CP (aged 6-12 years) were recruited. They were randomly allocated to receive 3 consecutive sessions of active or sham rTMS applied to the left dorsolateral prefrontal cortex (DLPFC). Participants were asked to perform the Box and Block Test (BBT) and Serial Subtraction Test (SST) separately or simultaneously before and immediately after each rTMS session.

resultsForty participants completed the study (22 in the active rTMS group). On day 3, significant enhancements were observed in SST scores for the active rTMS group compared to the sham group (single-task:14.4 ± 1.6 vs. 8.89 ± 1.8, p = 0.024; dual-task: 9.36 ± 1.0 vs. 3.89 ± 1.1, p = 0.001). Under the dual-task condition, the active rTMS group displayed a greater improvement in BBT scores than the sham group on day 3 (8.91 ± 1.03 vs. 3.83 ± 1.14, corrected p = 0.003). There were no notable differences between the two groups in the improvement of BBT scores under the single-task condition. No serious adverse events were reported.

conclusionThe rTMS applied to the left DLPFC is safe and effective in improving the performance of cognitive-motor dual-task in children with CP.

Indexed as

Cerebral PalsyCognitionPsychomotor PerformanceTranscranial Magnetic StimulationChildDorsolateral Prefrontal CortexFemaleHumansMaleCerebral palsyDual-task; cognitionMotor functionTranscranial magnetic stimulation

Identifiers

PMID40684180
PMCPMC12275326

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.