ArticleBMC oral health2025
Arginine-loaded mesoporous silica nanoparticles modified 3D-printed nanocomposite denture base resin with improved mechanical and antimicrobial properties.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Smart Mesoporous Silica Nanoparticle-Based Drug Delivery Systems: Recent Advances in Biomedical Applications, Wound Healing and Therapeutic Perspectives.Pharmaceutics · 2026Review
- Mesoporous and magnetic nanoparticle-based delivery of 1-hydroxyphenazine extracted from Pseudomonas aeruginosa enhances antimicrobial activity against different bacterial pathogens.Folia microbiologica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThree-dimensional (3D) printed denture base resin exhibits limitations including low wear resistance, poor strength, and the lack of antimicrobial property. This study investigated the mechanical and antimicrobial properties of arginine-loaded mesoporous silica nanoparticles (Arg@MSNs) modified 3D-printed denture resin.
methodsArg@MSNs were synthesized, characterized, and incorporated into resin matrix at 0.5, 1.0, and 2.5 wt%, unmodified resin was served as control. Specimens were fabricated according to test specifications. Surface roughness (Ra), color alteration (ΔE), flexural strength/modulus, hardness and antimicrobial efficacy against Streptococcus mutans and Candida albicans were assessed. Data were evaluated by one-way analysis of variance, followed by the Tukey honestly significant difference post hoc test, with a significance level set at 0.05.
resultsResults showed that Arg@MSNs exhibited sustained arginine release and nanoscale morphology. The 2.5 wt% group demonstrated the highest Ra and ΔE value, significantly higher than other groups (p < 0.05). Flexural strength and modulus significantly improved at 0.5 wt% and 1.0 wt% compared to the control (p < 0.05), but decreased at 2.5 wt%. Incorporation of Arg@MSNs at all levels increased hardness, significantly exceeding that of the control (p < 0.05). Antimicrobial performance significantly improved with higher concentrations of Arg@MSNs.
conclusionsThe addition of 1.0 wt% Arg@MSNs imparted synergistic enhancements in antimicrobial efficacy and mechanical properties to the 3D-printed nanocomposite, while maintaining clinically acceptable surface roughness and aesthetic performance. These findings demonstrated that Arg@MSNs modified 3D-printed nanocomposite denture base resin, by combining 3D-printed resin with nanotechnology, has promising potential for functionalized dental prostheses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.