Evidence map›Paper›PMID 40684123›Full record

ArticleBMC oral health2025

Preparation of high-quality pure titanium SLA surface and evaluation of its physicochemical and biological properties - in vitro experiments.

Qiqi Liu, Yujia Zhao, Junjiang Hao, Lin Qiu, Hanqi Su, Xinyu Wang, Yucheng Su

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PubMed Full text at PMC Publisher
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Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiqi LiuExperimental Center for Stomatological Engineering, Key Laboratory of Oral Biomedical Materials and Clinical Application, Stomatology Collage of Jiamusi University, Jiamusi University, Jiamusi, Heilongjiang Province, Heilongjiang, 154002, China.
Yujia ZhaoExperimental Center for Stomatological Engineering, Key Laboratory of Oral Biomedical Materials and Clinical Application, Stomatology Collage of Jiamusi University, Jiamusi University, Jiamusi, Heilongjiang Province, Heilongjiang, 154002, China.
Junjiang HaoBeijing CRS Medical Device Co., Ltd, Beijing, 102600, China.
Lin QiuCentral Laboratory, Peking University School and Hospital of Stomatology, Beijing, 100080, China.
Hanqi SuBeijing CRS Medical Device Co., Ltd, Beijing, 102600, China.
Xinyu WangExperimental Center for Stomatological Engineering, Key Laboratory of Oral Biomedical Materials and Clinical Application, Stomatology Collage of Jiamusi University, Jiamusi University, Jiamusi, Heilongjiang Province, Heilongjiang, 154002, China.
Yucheng SuExperimental Center for Stomatological Engineering, Key Laboratory of Oral Biomedical Materials and Clinical Application, Stomatology Collage of Jiamusi University, Jiamusi University, Jiamusi, Heilongjiang Province, Heilongjiang, 154002, China. yuchengsu@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to prepare high-quality sandblasted large-grit acid-etched surfaces of pure titanium and to evaluate their physicochemical and biological properties.

methodsWe investigated the acid-etching parameters of pure titanium under two sandblasting conditions, focusing on acid concentration, temperature, and time, utilizing an orthogonal experimental design. The optimal conditions for each sandblasted titanium surface were determined through range analysis, enabling the production of high-quality sandblasted large-grit acid-etched surfaces. Surface properties, including morphology and elemental composition, were assessed, along with biocompatibility tests for cell adhesion, proliferation, and osteogenic differentiation.

resultsFor sandblasted group a, the optimal acid-etching parameters were a mixture of 4.6 mol/L sulfuric acid and 0.814 mol/L hydrochloric acid at 60 °C for 60 min, which yielded a moderately rough surface (Group A: Sa = 1.30 ± 0.07μm). The optimal acid etching parameters for sandblasting group b were etching at 80 °C for 30 min in the same mixed solution to form a rough surface (Group B: Sa = 2.60 ± 0.10μm). Both surface treatments resulted in hydrophilicity and superior cell proliferation and osteogenic differentiation compared with those of the controls.

conclusionsDifferent parameters of large-particle sandblasting and acid etching treatments can create pure titanium surfaces with varying degrees of roughness. However, both of which demonstrate favorable physicochemical and biological properties.

Indexed as

Acid Etching, DentalTitaniumBiocompatible MaterialsCell AdhesionCell DifferentiationCell ProliferationHumansMaterials TestingMicroscopy, Electron, ScanningOsteoblastsOsteogenesisSulfuric AcidsSurface PropertiesBiocompatible Materialssulfuric acidSulfuric AcidsTitaniumAcid etchingDental implantsOrthogonal designOsseointegrationPure titanium

Identifiers

PMID40684123
PMCPMC12276656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.