Evidence map›Paper›PMID 40684101›Full record

SynthesisBMC oral health2025

Can the use of silver nanoparticles in dental implants increase its antimicrobial potency? - systematic review.

Brice Joseph, Nessma Sultan, Soher Nagi Jayash

Abstract readSystematic Review
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Usage of Silver Nanoparticles in Orthodontic Appliances.Materials (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brice JosephCollege of Medicine and Dentistry - Outreach Centre, Ulster University, Birmingham, UK.
Nessma SultanOral Biology department, Faculty of Dentistry, Mansoura University, Mansoura, 35516, Egypt. nesmasultan88@gmail.com.
Soher Nagi JayashRoslin Institute, University of Edinburgh, Edinburgh, UK. sjayash@ed.ac.uk.

Funding

the Biotechnology and Biological Sciences Research Council (BBSRC) BBS/E/RL/230001C
6 · The paper itself

Abstract

backgroundSilver nanoparticles (AgNPs) is a promising nanotechnological solution to prevent microbial colonization on dental implants, offering a promising avenue for combating implant-related infections and improving long-term treatment outcomes.

methodsUsing manual search and electronic databases such as PubMed Advanced Search and Google Scholar, a methodical search was carried out from 2013 to 2023 utilizing keywords, and inclusion and exclusion criteria to find pertinent papers addressing the research question "Can the use of silver nanoparticles in dental implants increase its antimicrobial potency?". Critical Appraisal analysis for this review was done using risk of bias tool for in vitro studies: QUIN tool.

resultsNine of the 122 articles that were retrieved underwent the three-step screening process before being chosen for the final analysis. QUIN Tool were used to evaluate the quality of the included in vitro studies. The summarized results from nine studies reveal the efficacy of AgNPs in inhibiting microorganisms and preventing biofilm formation on dental implants. In vitro tests demonstrate AgNPs' ability to hinder bacterial growth associated with peri-implantitis. Various techniques, including surface modifications and nanostructure incorporations, exhibit promising antibacterial effects.

conclusionsAgNPs show promise in inhibiting multidrug-resistant bacteria, enhancing dental implant biocompatibility, and reducing peri-implant diseases, benefiting clinical outcomes and limiting bacterial colonization.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsDental ImplantsMetal NanoparticlesSilverBiofilmsHumansPeri-ImplantitisAnti-Bacterial AgentsAnti-Infective AgentsDental ImplantsSilverDental implant biocompatibilityPeri-implantitisSilver nanoparticles

Identifiers

PMID40684101
PMCPMC12276661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.