Evidence map›Paper›PMID 40684051›Full record

ArticleScientific reports2025

Dosimetric evaluation of field parameters in VMAT for cervical cancer with inguinal lymphatic drainage extension.

Jing Zeng, Jinlong Hao, Jianguo Zhao, Peisong Sun

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Jing Zeng *Department of Gynecologic Oncology, Tianjin Institute of Gynaecology Obsterics, Tianjin Central Hospital of Gynaecology Obsterics, Tianjin, China.
Jinlong Hao *Department of Gynecologic Oncology, Tianjin Institute of Gynaecology Obsterics, Tianjin Central Hospital of Gynaecology Obsterics, Tianjin, China.
Jianguo ZhaoDepartment of Gynecologic Oncology, Tianjin Institute of Gynaecology Obsterics, Tianjin Central Hospital of Gynaecology Obsterics, Tianjin, China. zhaojianguozxfck@163.com.
Peisong SunDepartment of Gynecologic Oncology, Tianjin Institute of Gynaecology Obsterics, Tianjin Central Hospital of Gynaecology Obsterics, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For cervical cancer radiotherapy, patients requiring inguinal lymphatic drainage (ILD) extension fields pose challenges due to the large and complex target volume. To investigate the dosimetric effects of x-jaw width, jaw aperture position, and the number of arcs on volumetric modulated arc therapy (VMAT) plans for ILD extension fields, in order to optimize treatment planning. Thirty-nine patients were retrospectively included, and seven VMAT planning groups were created: OF (open field), X = 15/16/17/18 (jaw widths of 15-18 cm), SP (split-field, four arcs), and X = 15 M (jaw aperture moved toward the isocenter). Dosimetric parameters, including homogeneity index (HI), target coverage, and organs-at-risk (OARs) doses, were compared. The X = 15 plan achieved significantly lower intestinal, bladder, and rectal doses compared to the X = 17 and X = 18 plans (p < 0.05). The SP plan demonstrated superior HI and OARs sparing compared to the X = 15 plan, but required longer treatment times. The X = 15 M plan resulted in reduced edge doses but increased intestinal and bladder doses. For cervical cancer ILD extension fields, dual-arc VMAT plans with a 15 cm jaw width (X = 15) are recommended for optimal balance between target coverage and OARs sparing. Split-field plans may be considered if extended treatment time is acceptable.

Indexed as

Radiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedUterine Cervical NeoplasmsAdultAgedFemaleHumansMiddle AgedOrgans at RiskRadiometryRadiotherapy DosageRetrospective StudiesCervical cancerField parametersInguinal lymphatic drainage extended fieldVolumetric modulated arc therapy

Identifiers

PMID40684051
PMCPMC12276232

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.