ArticleNature communications2025
A legume cellulase required for rhizobial infection and colonization in root nodule symbiosis.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A recently evolved Nodulin recruited by NIN for root hair rhizobial infection in Medicago truncatula.The New phytologist · 2026Article
- Endophyte Bacillus sp. RE35 Enhances Cd Trap in Rice Roots Via Root Cell Wall Remodelling During Colonisation.Plant, cell & environment · 2026Article
- Silicon enhancement of nitrogen use efficiency in plants: insights from soil nitrogen transformation, plant nitrogen uptake, assimilation, and remobilization.Frontiers in plant science · 2026Review
- Root cell wall remodeling during symbiotic microbial colonization.Frontiers in plant science · 2026Review
- Symbiosome functionality in Medicago truncatula nodules requires continuous clearing of pectins from the symbiosome space.Nature communications · 2025Article
- The Lotus japonicus alpha-expansin EXPA1 is recruited during intracellular and intercellular rhizobial colonization.The Plant journal : for cell and molecular biology · 2025Article
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Authors and funding
4 authors.
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Abstract
In root nodule symbiosis, the accommodation of rhizobia in legumes necessitates extensive plant cell wall remodeling to build infection threads (ITs) for rhizobia travelling into nodules, and to subsequently release rhizobia from ITs to form nitrogen fixing symbiosomes. The molecular and cellular mechanisms underlying these processes are obscure. Here we report that Medicago truncatula Glycoside Hydrolase 9C2 (GH9C2) is required for both rhizobial infection and nodule colonization. The gh9c2-1 mutant exhibits incompetent nodules with disorganized ITs and defective rhizobial release, likely due to cellulose accumulation. GH9C2 localizes to IT wall and rhizobial release sites, and cellulase activity is indispensable for GH9C2 function. CBM49 domain of GH9C2 is required for rhizobial infection but not for rhizobial release. Furthermore, GH9C1and NPL act synergistically with GH9C2 in rhizobial infection. Our finding reveals transient IT-derived structures, the rhizobial release foci and uncovers a mechanism mediated by host cellulases for the symbiotic colonization by rhizobia.
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