Evidence map›Paper›PMID 40683760›Full record

ArticleTrends in parasitology2025

Rethinking parasitoid venoms: beyond immune suppression.

Abraham Y Kpirikai, Nicholas M Bretz, Nathan T Mortimer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abraham Y KpirikaiDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, USA.
Nicholas M BretzDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, USA.
Nathan T MortimerDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, USA. Electronic address: nathan.mortimer@oregonstate.edu.

Funding

Regulation of Host Signaling by Parasitoid Venom ProteinsR35GM133760 · NIGMS · OREGON STATE UNIVERSITY · PI MORTIMER, NATHAN TERRY · 2019 to 2023
$1.2M
A Novel Drosophila Model to Understand the Role of Innate Immunity in Alzheimer's DiseaseR03AG063314 · NIA · ILLINOIS STATE UNIVERSITY · PI MORTIMER, NATHAN TERRY · 2019 to 2020
$293k
NIA NIH HHS R03 AG063314NIGMS NIH HHS R35 GM133760
6 · The paper itself

Abstract

Parasitoid wasp venoms are widely studied for their immunosuppressive properties. Work by Dong et al. expands the venom repertoire to include manipulation of host metabolites with the discovery of the Leptopilina-specific venom lipase (LVL). LVL is an active lipase that converts host lipids to support parasitoid embryogenesis following infection.

Indexed as

Host-Parasite InteractionsLipaseWaspsWasp VenomsAnimalsLipaseWasp Venomsinsect venomlipaseparasitoid wasp

Identifiers

PMID40683760
PMCPMC12342344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.