Evidence map›Paper›PMID 40682793›Full record

ArticleCancer2025

Urban-rural disparities in lung cancer incidence and mortality patterns in Black and White populations.

Nadia Howlader, Kathleen A Cronin, Mandi Yu, Daniel Miller, Douglas R Lowy

Abstract read
In one paragraph

Article in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Review
  5. Article
  6. Cancer statistics, 2026.CA: a cancer journal for clinicians
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadia HowladerSurveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-1989-1478
Kathleen A CroninSurveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-7282-9323
Mandi YuSurveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0003-1281-6456
Daniel MillerInformation Management Services, Calverton, Maryland, USA.
Douglas R LowyNational Cancer Institute, Bethesda, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer mortality trends among Black and White populations and urban compared to rural populations are critical for assessing disparities in cancer outcomes.

methodsThis serial cross-sectional study used US national death certificate data from the National Center for Health Statistics and data from the National Program of Cancer Registries and Surveillance, Epidemiology, and End Results Program. The study analyzed lung cancer incidence (2001-2021) and mortality (1990-2021) trends by race, sex, and urban-rural status. Age-adjusted incidence and mortality rates and average annual percent changes (AAPCs) were estimated.

resultsSince 1990, lung cancer death rates have declined faster for Black men, which has reduced the gap with White men, but White women have consistently had higher rates than Black women. Rural areas showed higher incidence and mortality rates compared to urban areas. During 2013-2021, incidence rates declined similarly among urban and rural Black men (AAPC, -3.4 and -4.3, respectively) and White men (AAPC, -3.6 and -2.7, respectively). However, mortality rates decreased faster for urban Black men than for rural Black men (AAPC, -5.4 vs. -4.5) and for urban White men than for rural White men (AAPC, -4.8 vs. -4.0). Incidence and mortality rates declined faster for urban Black and White women than for their rural counterparts.

conclusionsAlthough the disparity in lung cancer death rates between Black and White men has narrowed, significant disparities persist between urban and rural populations. The more rapid decline in mortality rates in urban areas suggests that recent treatment advancements may be less accessible to rural populations.

Indexed as

Black or African AmericanHealth Status DisparitiesLung NeoplasmsRural PopulationUrban PopulationWhiteAdultAgedCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedMortalitySEER Programlung cancer incidencelung cancer mortalitySurveillance, Epidemiology, and End Results (SEER)urban–rural disparitiesWhite and Black populations

Identifiers

PMID40682793
PMCPMC12276023

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.