Evidence map›Paper›PMID 40682749›Full record

ArticleAging clinical and experimental research2025

Unveiling the hidden risks: 90-day mortality and complications in older adults with proximal femur fractures.

Clemens Roitzsch, Franziska Beyer, Klaus-Dieter Schaser, Roman Riedel, Marcel Mäder, Anne Postler

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Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clemens RoitzschUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany. Clemens.roitzsch@uniklinikum-dresden.de.
Franziska BeyerUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany.
Klaus-Dieter SchaserUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany.
Roman RiedelUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany.
Marcel MäderUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany.
Anne PostlerUniversity Center of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, TU Dresden, University of Technology, Fetscherst. 74, 01307, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.

aimsThe aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.

methodsBetween 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.

resultsOut of 1217 analyzed geriatric patients, 61% underwent surgery within 24 h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24 h after admission was associated with the development of wound infections (p = 0.022) and internal medicine-related complications (p = 0.002). DISCUSSION: While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.

conclusionThe mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors. CLINICAL TRIALS REGISTRATION: German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.

Indexed as

Femoral FracturesPostoperative ComplicationsAgedAged, 80 and overComorbidityFemaleHumansMaleProspective StudiesProximal Femoral FracturesRisk FactorsGeriatricMortalityProximal femur fractureRisk factors

Identifiers

PMID40682749
PMCPMC12276096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.