ArticleAging clinical and experimental research2025
Central and peripheral arterial stiffness and sarcopenia in hospitalized older adults.
Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association of cardio-ankle vascular index value with cardiovascular risk factors in elderly individuals.International journal of cardiology. Heart & vasculature · 2026Article
- Immune-mediated interactions between sarcopenia and atherosclerosis in aging.Immunity & ageing : I & A · 2025Review
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBoth sarcopenia and arterial wall stiffening are frequent findings among hospitalized older adults, and further insight should be gained to explore their pathophysiological mechanisms and possible correlations.
methods90 hospitalized geriatric patients (mean age 83.94 ± 6.6 years, 38.89% female, 36.7% sarcopenic) have been enrolled, and underwent clinical, comorbidity and biochemical assessment. Sarcopenia was investigated following the diagnostic algorithm according to European guidelines assessing muscular strength, using a portable dynamometer, and muscle mass by bio-impedance analysis (BIA); carotid-femoral pulse wave velocity (cfPWV), carotid-radial PWV (crPWV), femoral-pedal PWV (fpPWV) and cardio-ankle vascular index (CAVI) were obtained for each.
resultsSarcopenic patients (n = 33) were older (p < 0.01) than subjects without sarcopenia (n = 57). Sarcopenic patients presented higher CAVI (12.67 ± 3.12 vs. 10.91 ± 1.4, p < 0.01) and fpPWV, but not cfPWV and crPWV. In backward analysis muscle strength and comorbidity index resulted good indipendent variables of fpPWV (R
conclusionincreased indexes of arterial stiffness are shown in sarcopenic hospitalized older adults as compared to hospitalized patients without sarcopenia; peripheral arterial segments of the lower limb appeared to be more involved in the stiffening process, as compared to central segments.
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