Evidence map›Paper›PMID 40682733›Full record

ArticleInternational ophthalmology2025

How patients deal with side-effects of topical intraocular pressure-lowering medication in glaucoma: a cross-sectional study from a tertiary ophthalmology clinic.

Ante Krešo, Darko Batistić, Josip Vrdoljak, Ljubo Znaor, Ana Marušić

Abstract read
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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ante KrešoDepartment of Ophthalmology, University Hospital of Split, Spinčićeva 1, 21000, Split, Croatia.ORCID https://orcid.org/0000-0002-8186-9714
Darko BatistićDepartment of Ophthalmology, University Hospital of Split, Spinčićeva 1, 21000, Split, Croatia.ORCID https://orcid.org/0009-0005-4474-6650
Josip VrdoljakDepartment of Pathophysiology, School of Medicine, University of Split, Split, Croatia.ORCID https://orcid.org/0000-0001-8375-7233
Ljubo ZnaorDepartment of Ophthalmology, University Hospital of Split, Spinčićeva 1, 21000, Split, Croatia. ljubo.znaor@mefst.hr.ORCID https://orcid.org/0000-0002-0569-0181
Ana MarušićScience Department, University Hospital of Split, Split, Croatia.ORCID https://orcid.org/0000-0001-6272-0917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the knowledge, attitudes, and experiences of glaucoma patients about the side effects of intraocular pressure (IOP)-lowering medications in glaucoma, focusing on how these factors affect treatment adherence.

methodsWe conducted a cross-sectional survey during routine visits to glaucoma clinic, with participants aged 18 years or older on IOP-lowering medications for at least 6 months. The survey, consisting of 22 questions about various aspects of IOP-lowering medications and side effects.

resultsMost out of 398 analysed patients were not informed about side effects when IOP-lowering medication was prescribed, and 68.1% reported experiencing side effects. A significant number of participants reported changing IOP-lowering medications due to side effects. Higher self-reported knowledge about side effects was associated with lower concern (coef. = - 0.1636, P = 0.048) about side effects.

conclusionThe study identified significant gaps in patient education and support about IOP-lowering medications side effects. Better communication and education by healthcare providers could improve treatment adherence, consequentially enhancing clinical outcomes and quality of life for glaucoma patients.

Indexed as

Antihypertensive AgentsGlaucomaHealth Knowledge, Attitudes, PracticeIntraocular PressureAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMedication AdherenceMiddle AgedOphthalmic SolutionsQuality of LifeSurveys and QuestionnairesAntihypertensive AgentsOphthalmic SolutionsAdherenceEye dropsGlaucomaIOP-lowering medicationPatient educationSide effects

Identifiers

PMID40682733

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.