ArticleAging clinical and experimental research2025
Operationalizing Short Physical Performance Battery (SPPB) with muscle strength and power: predicting adverse events in older adults from the ilsirente study.
Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- A Multidomain Longitudinal Analysis of Frailty, Functional Limitation, Balance and Falls in Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- Reliability and Construct Validity of the Short Physical Performance Battery in Croatian Older Adults.Geriatrics (Basel, Switzerland) · 2026Article
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6 authors.
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Abstract
BACKGROUND AND
aimsThe present study examined associations between Short Physical Performance Battery (SPPB) indexes operationalized according to lower limb muscle strength and power and the incidence of adverse events in older community-dwellers.
methodsThis was a prospective cohort study of octogenarians who lived in the mountain community of the Sirente geographic area in Central Italy. Participants completed the SPPB under standardized conditions. Lower limb muscle power was estimated according to results from the 5-time sit-to-stand (5STS) test using validated equations. Then, four SPPB indexes were created by replacing 5STS test results with muscle power measures. Outcomes were assessed 24 months after baseline and included falls, fractures, and death.
resultsData of 255 older adults (mean age: 85.8 ± 4.8 years; women: 67.0%) were examined. Binary regression analysis indicated that conventional SPPB was significantly associated with the incidence of falls (Odds ratio [OR] = 0.841, [95% confidence interval [CI]] = 0.758, 0.934), fractures (OR = 0.837, 95%CI = 0.702, 0.998), and death (hazard ratio = 0.961, 95%CI = 0.934, 0.999). However, no significant results were found when SPPB was operationalized according to muscle power parameters. Area under the curve (AUC) results indicated that SPPB indexes had lower accuracy for distinguishing participants at higher risk of negative events. DISCUSSION AND
conclusionsResults of the present study indicate that conventional SPPB, but not SPPB indexes operationalized according to lower limb muscle power, was significantly associated with the incidence of negative events in older adults. However, SPPB indexes were not good to identify older adults at higher risk of experiencing negative events.
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