Evidence map›Paper›PMID 40682585›Full record

ArticleJACC. Case reports2025

Extensive Myocardial Calcifications Associated With Recent-Onset Renal Failure and Primary Hyperparathyroidism.

Rubens Groulez, Benjamin Longère, Alexandre Barbé, Marie Veron, Charles Benezech, François Pontana, David Montaigne, Augustin Coisne

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rubens GroulezUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
Benjamin LongèreUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
Alexandre BarbéOphtalmology Department, Lille University Hospital, Huriez Hospital, Lille, France.
Marie VeronDermatology Department, CHU Lille, Lille, France.
Charles BenezechPathology Department, Centre de Biologie Pathologie Pierre-Marie Degand, Lille, France.
François PontanaUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
David MontaigneUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
Augustin CoisneUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France; Cardiovascular Research Foundation, New York City, New York, USA. Electronic address: augustin.coisne@chu-lille.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac calcifications are a rare consequence of end-stage renal failure and hyperparathyroidism. CASE SUMMARY: A 35-year-old man with no prior medical history was admitted to our institution with sudden blindness in his right eye and severe renal failure. Ophthalmologic evaluation revealed central retinal artery occlusion with arterial calcifications. End-stage chronic renal failure was diagnosed. A positron emission tomography-computed tomography (CT) and a Tc-99m multiplex ion beam imaging scintigraphy confirmed hyperparathyroidism. Transthoracic echocardiography, magnetic resonance imaging, and cardiac CT identified significant myocardial calcifications and restrictive cardiomyopathy caused by hyperparathyroidism and renal failure. Management included dialysis and parathyroidectomy. DISCUSSION: This is the first human report to assess cardiac calcifications associated with hyperparathyroidism and end-stage renal failure with a strong correlation between transthoracic echocardiography, magnetic resonance imaging, and cardiac CT. TAKE-HOME MESSAGE: Calcium-phosphorus metabolic disorders and renal failure contribute to multiple systemic complications, including vascular disease, cardiomyopathy, and atrial fibrillation.

Indexed as

computed tomographydisorders of calcium metabolismechocardiography

Identifiers

PMID40682585
PMCPMC12371376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.