Evidence map›Paper›PMID 40682451›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2025

High-risk human papillomavirus cervical infection prevalence: a nationwide retrospective study comparing opportunistic and organised screening, France, 2020 to 2023.

Olivier Supplisson, Nicolas Tessandier, Mathilde Roussel, Stéphanie Haim-Boukobza, Sonia Burrel, Mircea T Sofonea, Samuel Alizon

Abstract readComparative Study
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olivier SupplissonSorbonne University, Paris, France.
Nicolas TessandierExposUM Institute, Université de Montpellier, MIVEGEC, Montpellier, France.
Mathilde RousselLaboratoire Cerba, pole infectiologie, Frépillon, France.
Stéphanie Haim-BoukobzaCerba HealthCare, Issy-les-Moulineaux, France.
Sonia BurrelCNRS UMR 5234, Fundamental Microbiology and Pathogenicity, Université de Bordeaux, Bordeaux, France.
Mircea T SofoneaDepartment of Anesthesiology, Critical Care, Intensive Care, Pain and Emergency Medicine, CHU Nîmes, Nîmes, France.
Samuel AlizonCenter for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, Université PSL, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDIn France, cervical cancer screening for females aged 30--65 years primarily tests for high-risk (HR) human papillomavirus (HPV) infections.AIMWe aimed to map the prevalence of cervical infections caused by HPV16 and/or 18, or by any of 12 other carcinogenic HPV genotypes and compare prevalence estimates from tests from spontaneous medical visits (opportunistic screening) or the national screening programme (organised screening).METHODSWe extracted data from a large network of biology laboratories, containing all available results from HR HPV tests performed between 1 January 2020 and 30 November 2023 in metropolitan France. A full hierarchical Bayesian model was used to compute spatially resolved expected prevalence maps at the postcode level.RESULTSThe analytic sample contained results of 362,963 HR HPV tests. Among samples positive for HPV16 and/or 18, 2.9% and 3.8% were from organised and opportunistic screening, respectively. Samples positive for other genotypes were 6.9% and 9.4%, respectively.During the last week of the study (week 48 2023), among females aged 30 years, opportunistic screening was associated with a greater expected prevalence of HPV16 and/or 18 and other genotypes in 97.2% and 99.9% of postcodes, respectively. The probability this percentage was lower among females aged 66 years was below 95% for both genotype groups.For organised screening, a pronounced north-west/south-east gradient in infection prevalence was found across France for both genotype groups, with hotspots located at the border with Italy, Spain and Switzerland.CONCLUSIONOpportunistic screening is associated with systematic inflation of HR HPV infection prevalence.

Indexed as

Early Detection of CancerHuman papillomavirus 16Human papillomavirus 18Mass ScreeningPapillomaviridaePapillomavirus InfectionsUterine Cervical NeoplasmsAdultAgedBayes TheoremFemaleFranceGenotypeHuman Papillomavirus VirusesHumansMiddle Agedcervical infection prevalenceGaussian Markov random fieldsGaussian random fieldshigh-risk HPVopportunistic screeningorganised screening

Identifiers

PMID40682451
PMCPMC12273260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.