ArticleScandinavian journal of medicine & science in sports2025
Quadriceps Morphology 6- to 60-Months After Anterior Cruciate Ligament Tear.
Article in Scandinavian journal of medicine & science in sports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Structural determinants of quadriceps atrophy following ACL injury: Evidence for fibre atrophy without fibre loss or overt peripheral denervation.The Journal of physiology · 2026Article
- Persistent Human Quadriceps Muscle Volume Deficits Following ACL Reconstruction Are Associated With No Detectable Between-Leg Differences in Vastus Lateralis Muscle Signaling at Rest or Immediately Following Resistance Exercise.Scandinavian journal of medicine & science in sports · 2026Article
- Quadriceps Morphology 6- to 60-Months After Anterior Cruciate Ligament Tear.Scandinavian journal of medicine & science in sports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to compare quadriceps morphology between legs and individuals with a first-time anterior cruciate ligament (ACL) tear and uninjured controls. This was an exploratory cross-sectional study. We enrolled participants who were aged 19-35 years, and 6-60 months after a first-time ACL tear as well as uninjured controls. Participants attended two sessions separated by a minimum of 7 days. Bilateral knee extensor concentric and eccentric strength and rate of torque development (RTD) were assessed at the first session, and bilateral vastus lateralis muscle biopsies were obtained at the second. Muscle fiber-type specific cross-sectional area (fCSA), fiber-type proportions, and extracellular matrix area were calculated. Between-limb and between-group differences were estimated using mixed-effects regression. 41 of 47 (87%) participants completed the study (n = 21 ACL, n = 20 control). ACL group participants were a median (range) of 23 months from injury, and 78% had undergone an ACL reconstruction. Uninjured group participants had greater knee extensor concentric strength (-39.3 Nm; 95% CI: -54.2, -20.5), eccentric strength (-30.2 Nm; 95% CI: -53.4, -11.6), and RTD (-0.16 Nm/ms; 95% CI: -0.33, -0.04). No between-group or between-limb differences in muscle fiber-type specific fCSA, fiber-type proportions, or extracellular matrix area were observed. Despite deficits in knee extensor muscle performance, no difference in vastus lateralis fiber-type specific CSA, fiber-type proportion, or extracellular matrix area was detected between individuals 6-60 months after an ACL tear and uninjured controls.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.