Evidence map›Paper›PMID 40682207›Full record

ArticlePsycho-oncology2025

Network Analysis of Anxiety in Prostate Cancer Patients.

Christopher F Sharpley, Rebecca J Williams, Vicki Bitsika, Wayne M Arnold, David R H Christie

Abstract read
In one paragraph

Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher F SharpleyBrain-Behaviour Research Group, University of New England, Armidale, Australia.ORCID 0000-0001-7922-4848
Rebecca J WilliamsBrain-Behaviour Research Group, University of New England, Armidale, Australia.
Vicki BitsikaBrain-Behaviour Research Group, University of New England, Armidale, Australia.
Wayne M ArnoldBrain-Behaviour Research Group, University of New England, Armidale, Australia.
David R H ChristieBrain-Behaviour Research Group, University of New England, Armidale, Australia.ORCID 0000-0001-5494-8751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA large proportion of prostate cancer (PCa) patients also report being anxious, which can impede their recovery and adversely influence their personal relationships.

aimsIn order to better understand the relationships between symptoms of anxiety in these men, with a view towards more informed treatments for anxiety, the network structure of the symptomatology for Generalised Anxiety Disorder (GAD) was examined in this study.

methodsA total of 425 PCa patients completed the GAD-7 and an extended version of that inventory (the GAD-10). Data were analysed via Network Analysis, Pearson correlation coefficients, and ANOVA.

resultsNetwork analysis and multidimensional scaling indicated that being unable to control worry was the most central symptom for these men, and that several sets of GAD symptoms were closely associated with each other. These included worrying, inability to relax, and restlessness. Other anxiety symptoms such as sleeping problems, difficulty concentrating, and feeling tyred were less well-related with the remainder of the network. Implications for clinical practice were derived from the relationships between individual anxiety symptoms and the overall anxiety network by examining node predictability, and focused upon helping these men to 'switch off' from their worry by engaging in mutually-incompatible behaviours.

conclusionsThe use of total anxiety inventory scores fails to identify the underlying network structure of anxiety in PCa patients. By finding the central GAD symptom of being unable to control their worry, more individually-focussed anti-anxiety treatments might be developed and offered to these men.

Indexed as

AnxietyAnxiety DisordersProstatic NeoplasmsAgedAged, 80 and overHumansMaleMiddle AgedSurveys and Questionnairesanxietycancernetworkoncologyprostate

Identifiers

PMID40682207
PMCPMC12274292

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.