Evidence map›Paper›PMID 40682129›Full record

ArticleMalaria journal2025

Evaluation of anti-malarial treatment for elimination of malaria in South West Ethiopia: a concurrent triangulation design for prompt decision.

Mathewos Alemu Gebremichael, Tadesse Gebremedhin, Wondwossen Niguse, Girma Mamo, Bezuayehu Alemayehu, Ephrem Negeri, Ibrahim Temam, Haile Zewude, Tamerat Bogale, Endale Sahile and 1 more

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mathewos Alemu GebremichaelDepartment of Public Health, College of Health Sciences, Bonga University, Bonga, Ethiopia. alemumathewos2017@gmail.com.
Tadesse GebremedhinDepartment of Public Health, College of Health Sciences, Bonga University, Bonga, Ethiopia.
Wondwossen NiguseDepartment of Midwifery, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Aman, Ethiopia.
Girma MamoMizan-Aman College of Health Sciences, Mizan Aman, Ethiopia.
Bezuayehu AlemayehuDepartment of Environmental Health, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Aman, Ethiopia.
Ephrem NegeriSouthwest Ethiopian Peoples Regional Health Bureau, Tarcha Dawro, Ethiopia.
Ibrahim TemamSouthwest Ethiopian Peoples Regional Health Bureau, Tarcha Dawro, Ethiopia.
Haile ZewudeSouthwest Ethiopian Peoples Regional Health Bureau, Tarcha Dawro, Ethiopia.
Tamerat BogalePublic Health Institute, Southwest Ethiopian Peoples Regional Health Bureau, Tarcha Dawro, Ethiopia.
Endale SahileDiseases Prevention and Health Promotion Directorate, Southwest Ethiopian Peoples Regional Health Bureau, Tarcha Dawro, Ethiopia.
Erkyihun PawlosDepartment of Medicine, Mizan Tepi University, Mizan Aman, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria case management is a vital component of strategies to ensure malaria elimination programme. Despite continuous preventive strategies in place, malaria remains a major public health problem in resource-limited countries particularly in Ethiopia due to treatment-related problems. Hence, this study aimed to determine the level of adherence to malaria diagnosis and treatment guidelines among healthcare providers working in the public health facilities in Southwest Ethiopian Peoples Regional State (SWEPRS).

methodsA facility-based cross-sectional study triangulated with qualitative inquiry was applied from March 2024 and July 2024. A multi-stage stratified and purposive sampling technique was used for the quantitative and qualitative study, respectively. Data were collected by the records review, Focus Group Discussions (FGDs), and In-depth Interviews (IDIs). The adherence of healthcare providers was evaluated according to recommendations of the current malaria diagnosis and treatment guidelines. The findings in the qualitative analysis were presented in the thematic analysis and triangulated with the quantitative findings.

results1,684 patient cards were reviewed. The mean age of patients was 20.99 (± 15.61) years. 1,616 (95.96%) patients were screened through microscopy and/or multispecies rapid diagnostic tests (RDT). The overall adherence of healthcare providers to the updated malaria treatment standards was 36.99% (95%CI: 33.93-38.52%) and the majority, 982 (58.31%) were diagnosed with Plasmodium falciparum followed by Plasmodium vivax, and mixed infections. Shortage of anti-malarial drugs was reported as the foremost barrier followed by lack of training on the updated malaria case management guideline, shortage of health professionals, and lack of laboratory materials. In addition, shortage of electric supply, shortage of computers, shortage of outpatient department (OPD) rooms, lack of transport, distance from a health facility, community resistance, improper use of prescribed anti-malarial drugs, perceived inefficacy of drugs, inability to afford the anti-malarial drugs, lack of new malaria case management guideline, lack of private pharmacy, language barriers, and poor quality of Giemsa, were identified barriers.

conclusionsThe adherence level of healthcare providers was found to be low. Hence, ensuring the availability of all nationally recommended anti-malarial drugs and supplies, qualified health professionals, providing continuous training, strengthening continuous follow-up and supervision in the public health facilities are recommended to improve the adherence level of health professionals to national malaria treatment guideline.

Indexed as

AntimalarialsDisease EradicationGuideline AdherenceHealth PersonnelMalariaMalaria, FalciparumMalaria, VivaxAdolescentAdultCase ManagementChildChild, PreschoolCross-Sectional StudiesEthiopiaFemaleHumansAntimalarialsAdherenceEthiopiaGuidelineMalariaPublic HealthSouthwest

Identifiers

PMID40682129
PMCPMC12273387

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.