Evidence map›Paper›PMID 40682105›Full record

ArticleJournal of medical case reports2025

Atypical development and swift resolution of an ulcerated hemangioma: a case report.

Konstantine Chakhunashvili, Eka Kvirkvelia, Davit G Chakhunashvili

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Konstantine ChakhunashviliCaucasus University, Tbilisi, Georgia. kchakhunashvili@cu.edu.ge.ORCID http://orcid.org/0000-0003-0939-9479
Eka KvirkveliaCaucasus University, Tbilisi, Georgia.
Davit G ChakhunashviliChildren's Clinic After I. Tsitsishvili, Tbilisi, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfantile hemangiomas are considered as the most common benign vascular tumors in pediatric patients. Ulceration is one of the most frequent complications that typically occur at 2-3 months after birth. CASE PRESENTATION: A Caucasian Georgian male infant started to develop a hemangioma at 5 days old. At 3 weeks old, a pediatrician diagnosed it, and the patient was referred to a dermatologist. A week after starting initial treatment, at 4 weeks of age, the hemangioma ulcerated. Despite changing the initial treatment, the ulceration worsened. At 6 weeks old, topical timolol and mupirocin were initiated, leading to complete healing within 4 weeks. Timolol is still being applied, and follow-up visits showed no further ulceration.

conclusionAlthough the exact cause of the unusual ulcer development is unknown, we advise physicians to avoid prescribing topical ointments that have not been proven effective and safe for treating hemangioma.

Indexed as

HemangiomaMupirocinSkin NeoplasmsSkin UlcerTimololAdrenergic beta-AntagonistsAnti-Bacterial AgentsHumansInfantInfant, NewbornMaleTreatment OutcomeAdrenergic beta-AntagonistsAnti-Bacterial AgentsMupirocinTimololInfantile hemangiomaMupirocinTimololUlceration

Identifiers

PMID40682105
PMCPMC12275418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.