Evidence map›Paper›PMID 40681952›Full record

ArticlePediatric surgery international2025

Early versus delayed repair in patients with anorectal malformation with rectoperineal fistula: impact on short-term complications and midterm and long-term bowel function.

Xianming Xiao, Wei Feng, Chenzhu Xiang, Liang Yuan, Zhili Wang, Jinping Hou, Yi Wang

Abstract readComparative Study
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In one paragraph

Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xianming XiaoDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
Wei FengDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
Chenzhu XiangDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
Liang YuanDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
Zhili WangDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
Jinping HouDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China. sin1011@163.com.
Yi WangDepartment of General and Neonatal Surgery, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China. wy757311@Hotmail.com.

Funding

National Clinical Research Center for Child Health and Disorders, Children's Hospital of Chongqing Medical University NCRCCHD-2022-GP-04Program for Youth Innovation in Future Medicine, Chongqing Medical University W0125
6 · The paper itself

Abstract

backgroundThis study aims to investigate the impact of early versus delayed repair on early postoperative complications and midterm and long-term bowel function in ARM patients with rectoperineal fistula.

methodsA total of 568 ARM patients with rectoperineal fistula who underwent cutback anoplasty were identified at our hospital from 2015 to 2021. Early repair was defined as an anoplasty performed at or before 28 days of age. Delayed repair was defined as occurring after this period.

results267 patients were finally enrolled, with 171 males and 96 females. 129 (48.3%) underwent early repair and 138 (51.7%) delayed repair. Early postoperative complication rates showed no significant difference between the two groups (0% vs. 0.7%, P = 1.000). No wound infections or dehiscence occurred in either group within 6 months postoperatively. The median Rintala score did not differ significantly between the early and delayed groups (20 vs. 20, P = 0.272). Based on the Krickenbeck classification, there were no significant differences between the groups regarding constipation, soiling, or voluntary bowel movements (P > 0.05).

conclusionsEarly and delayed repair have no significant impact on early postoperative complications and midterm and long-term bowel function in ARM patients with rectoperineal fistula. Neonatal cutback anoplasty is safe and effective for stable patients without major comorbidities, offering a favorable prognosis.

Indexed as

Anorectal MalformationsPostoperative ComplicationsRectal FistulaTime-to-TreatmentChild, PreschoolFemaleHumansInfantInfant, NewbornMalePerineumRetrospective StudiesTime FactorsTreatment OutcomeAnorectal malformationBowel functionCutback anoplastyPrognosisRectoperineal fistulaSurgical time

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.