Evidence map›Paper›PMID 40681909›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

The global, regional, and national disease burden of laryngeal cancer attributable to high alcohol use from 1990 to 2021: a global burden of disease study.

Xiao-Ting Tong, Min-Li Zhang, Yun Liu, Rong Xiang, Hai-Lin Li, Chang-Hua Wang, Ting Zhu, Zhi-Feng Deng

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Global burden of alcohol-attributable laryngeal cancer: reflections on trends, risk, and research gaps.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xiao-Ting Tong *Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China.
Min-Li Zhang *Yaxin School of Nursing, Wuhan Institute of Design and Sciences, Wuhan, 430060, Hubei, China.
Yun Liu *Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China.
Rong XiangResearch Institute of Otolaryngologyï¿¿Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China.
Hai-Lin LiDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China.
Chang-Hua WangYaxin School of Nursing, Wuhan Institute of Design and Sciences, Wuhan, 430060, Hubei, China.
Ting Zhu *Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China. 18071717073@189.cn.
Zhi-Feng Deng *Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei, China. dzf070124025@163.com.

Funding

China Charity Federation ZKL-KY-2034-007Guiding Project of Scientific Research Plan of Hubei Provincial Department of Education of China B2023382Hubei Provincial Natural Science Foundation of China 2024AFB768
6 · The paper itself

Abstract

purposeThis study utilized data from the Global Burden of Disease (GBD) 2021 database to comprehensively analyze the global burden of laryngeal cancer (LC) attributable to high alcohol use from 1990 to 2021, and projections to 2050.

methodsData on death, disability adjusted of life years (DALYs), age-standardized death rate (ASDR), and age-standardized DALYs rate of LC attributable to high alcohol use were retrieved from the GBD 2021. Trend analysis used the estimated annual percentage change (EAPC). Death and DALYs were stratified according to social demographics index (SDI), age, gender, region, and countries. Auto-regressive integrated moving average (ARIMA) models provided future projections.

resultsBy 2021, global deaths of LC attributable to high alcohol use had slightly increased compared to 1990.The EAPCs for ASDR and age-standardized DALYs rate were - 1.48 and - 1.70, respectively. Males were high-risk populations and low-middle SDI regions was high-risk areas. The disease burden of LC attributable to high alcohol use varied considerably across the GBD regions and the countries. ARIMA model predicted results showed that the global deaths and DALYs cases would still increase from 2022 to 2050.

conclusionBetween 1990 and 2021, while the overall burden of high alcohol use-related LC was gradually decreasing, marked regional and gender disparities persist. The annual number of LC deaths attributed to high alcohol use continues to rise, particularly in males and low-middle SDI regions. Highlights the need for more effective public health policies targeting high-risk regions and populations to reduce alcohol-related LC burden.

Indexed as

Alcohol DrinkingGlobal Burden of DiseaseLaryngeal NeoplasmsSocial Determinants of HealthAdultAgedAged, 80 and overDatabases, FactualDisability-Adjusted Life YearsFemaleForecastingGeographyHealth Status DisparitiesHealth SurveysHumansMaleDALYsDeathDisease burdenGBDHigh alcohol useLaryngeal cancer

Identifiers

PMID40681909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.